NAD(P)-DEPENDENT DEHYDROGENASE ACTIVITY IN PERIPHERAL BLOOD LYMPHOCYTES OF INFANTS WITH ENLARGEMENT OF PHARYNGEAL TONSILS

We have observed and examined 57 children 1 to 3 years old diagnosed with enlargement of pharyngeal tonsils. A control group was presented by 35 healthy children. Bioluminescence technique was applied for studying NAD(P)-dependent dehydrogenase activity in peripheral blood lymphocytes. Activation of...

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Autores principales:	L. M. Kurtasova, A. R. Shmidt, T. V. Lubnina
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	lymphocytes enzymes pharyngeal tonsil enlargement Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/4a621e4d10ef4632b6578cadd8813103
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id	oai:doaj.org-article:4a621e4d10ef4632b6578cadd8813103
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spelling	oai:doaj.org-article:4a621e4d10ef4632b6578cadd88131032021-11-18T08:03:43ZNAD(P)-DEPENDENT DEHYDROGENASE ACTIVITY IN PERIPHERAL BLOOD LYMPHOCYTES OF INFANTS WITH ENLARGEMENT OF PHARYNGEAL TONSILS1563-06252313-741X10.15789/1563-0625-2014-4-381-384https://doaj.org/article/4a621e4d10ef4632b6578cadd88131032014-08-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/705https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XWe have observed and examined 57 children 1 to 3 years old diagnosed with enlargement of pharyngeal tonsils. A control group was presented by 35 healthy children. Bioluminescence technique was applied for studying NAD(P)-dependent dehydrogenase activity in peripheral blood lymphocytes. Activation of aerobic respiration and increasing activity of pentose phosphate cycle-dependent plastic processes were registered in blood lymphocytes of children with hypertrophic pharyngeal tonsils; along with decreased function of malate-aspartate shunt in energy metabolism of the cells, diminished anaerobic reaction of NADHdependent LDH, lower interaction between Krebs cycle and reactions of amino acid metabolism, and reduced activity of glutathione reductase.L. M. KurtasovaA. R. ShmidtT. V. LubninaSPb RAACIarticlelymphocytesenzymespharyngeal tonsil enlargementImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 16, Iss 4, Pp 381-384 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	lymphocytes enzymes pharyngeal tonsil enlargement Immunologic diseases. Allergy RC581-607
spellingShingle	lymphocytes enzymes pharyngeal tonsil enlargement Immunologic diseases. Allergy RC581-607 L. M. Kurtasova A. R. Shmidt T. V. Lubnina NAD(P)-DEPENDENT DEHYDROGENASE ACTIVITY IN PERIPHERAL BLOOD LYMPHOCYTES OF INFANTS WITH ENLARGEMENT OF PHARYNGEAL TONSILS
description	We have observed and examined 57 children 1 to 3 years old diagnosed with enlargement of pharyngeal tonsils. A control group was presented by 35 healthy children. Bioluminescence technique was applied for studying NAD(P)-dependent dehydrogenase activity in peripheral blood lymphocytes. Activation of aerobic respiration and increasing activity of pentose phosphate cycle-dependent plastic processes were registered in blood lymphocytes of children with hypertrophic pharyngeal tonsils; along with decreased function of malate-aspartate shunt in energy metabolism of the cells, diminished anaerobic reaction of NADHdependent LDH, lower interaction between Krebs cycle and reactions of amino acid metabolism, and reduced activity of glutathione reductase.
format	article
author	L. M. Kurtasova A. R. Shmidt T. V. Lubnina
author_facet	L. M. Kurtasova A. R. Shmidt T. V. Lubnina
author_sort	L. M. Kurtasova
title	NAD(P)-DEPENDENT DEHYDROGENASE ACTIVITY IN PERIPHERAL BLOOD LYMPHOCYTES OF INFANTS WITH ENLARGEMENT OF PHARYNGEAL TONSILS
title_short	NAD(P)-DEPENDENT DEHYDROGENASE ACTIVITY IN PERIPHERAL BLOOD LYMPHOCYTES OF INFANTS WITH ENLARGEMENT OF PHARYNGEAL TONSILS
title_full	NAD(P)-DEPENDENT DEHYDROGENASE ACTIVITY IN PERIPHERAL BLOOD LYMPHOCYTES OF INFANTS WITH ENLARGEMENT OF PHARYNGEAL TONSILS
title_fullStr	NAD(P)-DEPENDENT DEHYDROGENASE ACTIVITY IN PERIPHERAL BLOOD LYMPHOCYTES OF INFANTS WITH ENLARGEMENT OF PHARYNGEAL TONSILS
title_full_unstemmed	NAD(P)-DEPENDENT DEHYDROGENASE ACTIVITY IN PERIPHERAL BLOOD LYMPHOCYTES OF INFANTS WITH ENLARGEMENT OF PHARYNGEAL TONSILS
title_sort	nad(p)-dependent dehydrogenase activity in peripheral blood lymphocytes of infants with enlargement of pharyngeal tonsils
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/4a621e4d10ef4632b6578cadd8813103
work_keys_str_mv	AT lmkurtasova nadpdependentdehydrogenaseactivityinperipheralbloodlymphocytesofinfantswithenlargementofpharyngealtonsils AT arshmidt nadpdependentdehydrogenaseactivityinperipheralbloodlymphocytesofinfantswithenlargementofpharyngealtonsils AT tvlubnina nadpdependentdehydrogenaseactivityinperipheralbloodlymphocytesofinfantswithenlargementofpharyngealtonsils
_version_	1718422414369488896

NAD(P)-DEPENDENT DEHYDROGENASE ACTIVITY IN PERIPHERAL BLOOD LYMPHOCYTES OF INFANTS WITH ENLARGEMENT OF PHARYNGEAL TONSILS

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