Rare variants in ischemic stroke: an exome pilot study.

Rare variants in ischemic stroke: an exome pilot study.

The genetic architecture of ischemic stroke is complex and is likely to include rare or low frequency variants with high penetrance and large effect sizes. Such variants are likely to provide important insights into disease pathogenesis compared to common variants with small effect sizes. Because a...

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Bibliographic Details
Main Authors: John W Cole, O Colin Stine, Xinyue Liu, Abhishek Pratap, Yuching Cheng, Luke J Tallon, Lisa K Sadzewicz, Nicole Dueker, Marcella A Wozniak, Barney J Stern, James F Meschia, Braxton D Mitchell, Steven J Kittner, Jeffrey R O'Connell
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/4a6c4e5b22034bc4be3ca390a8735b34
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Internet

https://doaj.org/article/4a6c4e5b22034bc4be3ca390a8735b34

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