In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties
Regulated exocytosis of neuronal synaptic vesicles is substantially faster than that of endocrine dense core vesicles despite similar molecular machineries. Here authors compare SNARE-mediated fusion of purified synaptic vesicles with insulin vesicles and see disparities in calcium-triggered fusion...
Guardado en:
Autores principales: | Alex J. B. Kreutzberger, Volker Kiessling, Christopher Stroupe, Binyong Liang, Julia Preobraschenski, Marcelo Ganzella, Mark A. B. Kreutzberger, Robert Nakamoto, Reinhard Jahn, J. David Castle, Lukas K. Tamm |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/4a79a606ae254e35b295a19f8e1dafc2 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Conserved arginine residues in synaptotagmin 1 regulate fusion pore expansion through membrane contact
por: Sarah B. Nyenhuis, et al.
Publicado: (2021) -
Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion
por: Sung-Tae Yang, et al.
Publicado: (2016) -
Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes
por: Sabine Wittig, et al.
Publicado: (2021) -
Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi
por: Javier Emperador-Melero, et al.
Publicado: (2018) -
The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast synaptic vesicle fusion
por: Chad Paul Grabner, et al.
Publicado: (2021)