Electrooxidation enables highly regioselective dearomative annulation of indole and benzofuran derivatives

Enriching the chemical space of polycyclic heterocycles is of high value in chemical biology. Here, the authors report an electrooxidative protocol for the regioselective dearomative annulation of indoles and benzofurans under undivided cell conditions and obtain five- to eight-membered fused hetero...

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Autores principales: Kun Liu, Wenxu Song, Yuqi Deng, Huiyue Yang, Chunlan Song, Takfaoui Abdelilah, Shengchun Wang, Hengjiang Cong, Shan Tang, Aiwen Lei
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/4a79fff87c114e7ba6146878e175df09
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spelling oai:doaj.org-article:4a79fff87c114e7ba6146878e175df092021-12-02T14:42:30ZElectrooxidation enables highly regioselective dearomative annulation of indole and benzofuran derivatives10.1038/s41467-019-13829-42041-1723https://doaj.org/article/4a79fff87c114e7ba6146878e175df092020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13829-4https://doaj.org/toc/2041-1723Enriching the chemical space of polycyclic heterocycles is of high value in chemical biology. Here, the authors report an electrooxidative protocol for the regioselective dearomative annulation of indoles and benzofurans under undivided cell conditions and obtain five- to eight-membered fused heterocycles.Kun LiuWenxu SongYuqi DengHuiyue YangChunlan SongTakfaoui AbdelilahShengchun WangHengjiang CongShan TangAiwen LeiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kun Liu
Wenxu Song
Yuqi Deng
Huiyue Yang
Chunlan Song
Takfaoui Abdelilah
Shengchun Wang
Hengjiang Cong
Shan Tang
Aiwen Lei
Electrooxidation enables highly regioselective dearomative annulation of indole and benzofuran derivatives
description Enriching the chemical space of polycyclic heterocycles is of high value in chemical biology. Here, the authors report an electrooxidative protocol for the regioselective dearomative annulation of indoles and benzofurans under undivided cell conditions and obtain five- to eight-membered fused heterocycles.
format article
author Kun Liu
Wenxu Song
Yuqi Deng
Huiyue Yang
Chunlan Song
Takfaoui Abdelilah
Shengchun Wang
Hengjiang Cong
Shan Tang
Aiwen Lei
author_facet Kun Liu
Wenxu Song
Yuqi Deng
Huiyue Yang
Chunlan Song
Takfaoui Abdelilah
Shengchun Wang
Hengjiang Cong
Shan Tang
Aiwen Lei
author_sort Kun Liu
title Electrooxidation enables highly regioselective dearomative annulation of indole and benzofuran derivatives
title_short Electrooxidation enables highly regioselective dearomative annulation of indole and benzofuran derivatives
title_full Electrooxidation enables highly regioselective dearomative annulation of indole and benzofuran derivatives
title_fullStr Electrooxidation enables highly regioselective dearomative annulation of indole and benzofuran derivatives
title_full_unstemmed Electrooxidation enables highly regioselective dearomative annulation of indole and benzofuran derivatives
title_sort electrooxidation enables highly regioselective dearomative annulation of indole and benzofuran derivatives
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/4a79fff87c114e7ba6146878e175df09
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AT aiwenlei electrooxidationenableshighlyregioselectivedearomativeannulationofindoleandbenzofuranderivatives
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