Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair

Neutrophils and macrophages are both involved in the initiation of inflammation, but whether and how they may participate in inflammation resolution is unclear. Here the authors show that neutrophils may mediate the conversion of macrophage into a pro-resolution phenotype via reactive oxygen species...

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Autores principales: Wenting Yang, Yuandong Tao, Yan Wu, Xinyuan Zhao, Weijie Ye, Dianyuan Zhao, Ling Fu, Caiping Tian, Jing Yang, Fuchu He, Li Tang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/4a867b1d364648da86d4860a9748b0ec
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spelling oai:doaj.org-article:4a867b1d364648da86d4860a9748b0ec2021-12-02T15:35:17ZNeutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair10.1038/s41467-019-09046-82041-1723https://doaj.org/article/4a867b1d364648da86d4860a9748b0ec2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09046-8https://doaj.org/toc/2041-1723Neutrophils and macrophages are both involved in the initiation of inflammation, but whether and how they may participate in inflammation resolution is unclear. Here the authors show that neutrophils may mediate the conversion of macrophage into a pro-resolution phenotype via reactive oxygen species production to promote liver repair.Wenting YangYuandong TaoYan WuXinyuan ZhaoWeijie YeDianyuan ZhaoLing FuCaiping TianJing YangFuchu HeLi TangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wenting Yang
Yuandong Tao
Yan Wu
Xinyuan Zhao
Weijie Ye
Dianyuan Zhao
Ling Fu
Caiping Tian
Jing Yang
Fuchu He
Li Tang
Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair
description Neutrophils and macrophages are both involved in the initiation of inflammation, but whether and how they may participate in inflammation resolution is unclear. Here the authors show that neutrophils may mediate the conversion of macrophage into a pro-resolution phenotype via reactive oxygen species production to promote liver repair.
format article
author Wenting Yang
Yuandong Tao
Yan Wu
Xinyuan Zhao
Weijie Ye
Dianyuan Zhao
Ling Fu
Caiping Tian
Jing Yang
Fuchu He
Li Tang
author_facet Wenting Yang
Yuandong Tao
Yan Wu
Xinyuan Zhao
Weijie Ye
Dianyuan Zhao
Ling Fu
Caiping Tian
Jing Yang
Fuchu He
Li Tang
author_sort Wenting Yang
title Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair
title_short Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair
title_full Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair
title_fullStr Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair
title_full_unstemmed Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair
title_sort neutrophils promote the development of reparative macrophages mediated by ros to orchestrate liver repair
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/4a867b1d364648da86d4860a9748b0ec
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