Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair
Neutrophils and macrophages are both involved in the initiation of inflammation, but whether and how they may participate in inflammation resolution is unclear. Here the authors show that neutrophils may mediate the conversion of macrophage into a pro-resolution phenotype via reactive oxygen species...
Guardado en:
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/4a867b1d364648da86d4860a9748b0ec |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:4a867b1d364648da86d4860a9748b0ec |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:4a867b1d364648da86d4860a9748b0ec2021-12-02T15:35:17ZNeutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair10.1038/s41467-019-09046-82041-1723https://doaj.org/article/4a867b1d364648da86d4860a9748b0ec2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09046-8https://doaj.org/toc/2041-1723Neutrophils and macrophages are both involved in the initiation of inflammation, but whether and how they may participate in inflammation resolution is unclear. Here the authors show that neutrophils may mediate the conversion of macrophage into a pro-resolution phenotype via reactive oxygen species production to promote liver repair.Wenting YangYuandong TaoYan WuXinyuan ZhaoWeijie YeDianyuan ZhaoLing FuCaiping TianJing YangFuchu HeLi TangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Wenting Yang Yuandong Tao Yan Wu Xinyuan Zhao Weijie Ye Dianyuan Zhao Ling Fu Caiping Tian Jing Yang Fuchu He Li Tang Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair |
description |
Neutrophils and macrophages are both involved in the initiation of inflammation, but whether and how they may participate in inflammation resolution is unclear. Here the authors show that neutrophils may mediate the conversion of macrophage into a pro-resolution phenotype via reactive oxygen species production to promote liver repair. |
format |
article |
author |
Wenting Yang Yuandong Tao Yan Wu Xinyuan Zhao Weijie Ye Dianyuan Zhao Ling Fu Caiping Tian Jing Yang Fuchu He Li Tang |
author_facet |
Wenting Yang Yuandong Tao Yan Wu Xinyuan Zhao Weijie Ye Dianyuan Zhao Ling Fu Caiping Tian Jing Yang Fuchu He Li Tang |
author_sort |
Wenting Yang |
title |
Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair |
title_short |
Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair |
title_full |
Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair |
title_fullStr |
Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair |
title_full_unstemmed |
Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair |
title_sort |
neutrophils promote the development of reparative macrophages mediated by ros to orchestrate liver repair |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/4a867b1d364648da86d4860a9748b0ec |
work_keys_str_mv |
AT wentingyang neutrophilspromotethedevelopmentofreparativemacrophagesmediatedbyrostoorchestrateliverrepair AT yuandongtao neutrophilspromotethedevelopmentofreparativemacrophagesmediatedbyrostoorchestrateliverrepair AT yanwu neutrophilspromotethedevelopmentofreparativemacrophagesmediatedbyrostoorchestrateliverrepair AT xinyuanzhao neutrophilspromotethedevelopmentofreparativemacrophagesmediatedbyrostoorchestrateliverrepair AT weijieye neutrophilspromotethedevelopmentofreparativemacrophagesmediatedbyrostoorchestrateliverrepair AT dianyuanzhao neutrophilspromotethedevelopmentofreparativemacrophagesmediatedbyrostoorchestrateliverrepair AT lingfu neutrophilspromotethedevelopmentofreparativemacrophagesmediatedbyrostoorchestrateliverrepair AT caipingtian neutrophilspromotethedevelopmentofreparativemacrophagesmediatedbyrostoorchestrateliverrepair AT jingyang neutrophilspromotethedevelopmentofreparativemacrophagesmediatedbyrostoorchestrateliverrepair AT fuchuhe neutrophilspromotethedevelopmentofreparativemacrophagesmediatedbyrostoorchestrateliverrepair AT litang neutrophilspromotethedevelopmentofreparativemacrophagesmediatedbyrostoorchestrateliverrepair |
_version_ |
1718386594177613824 |