Human islets contain four distinct subtypes of β cells

Dysfunction or loss of insulin-secreting β cells in the pancreas is a hallmark of diabetes. Here, Dorrell et al.identify four subpopulations of β cells in humans, which differ in gene expression and insulin secretion kinetics, and the abundance of which is altered in patients with type 2 diabetes.

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Detalles Bibliográficos
Autores principales: Craig Dorrell, Jonathan Schug, Pamela S. Canaday, Holger A. Russ, Branden D. Tarlow, Maria T. Grompe, Tamara Horton, Matthias Hebrok, Philip R. Streeter, Klaus H. Kaestner, Markus Grompe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/4a8e221047c74cf29f151b27d212cf85
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