The effect of low glycemic index diet on the reproductive and clinical profile in women with polycystic ovarian syndrome: A systematic review and meta-analysis

Background: Treatment for polycystic ovary syndrome (PCOS) usually initiates with a series of lifestyle modifications such as diet, weight loss, and exercise. Aims: We, therefore, conducted this meta-analysis to systematically review and evaluate the possible benefits of LGD on a range of anthropome...

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Autores principales: Najmieh Saadati, Fatemeh Haidari, Mojgan Barati, Roshan Nikbakht, Golshan Mirmomeni, Fakher Rahim
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Publicado: Elsevier 2021
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spelling oai:doaj.org-article:4a94f31cc23943c39a86f8ecda0bad202021-12-02T05:02:43ZThe effect of low glycemic index diet on the reproductive and clinical profile in women with polycystic ovarian syndrome: A systematic review and meta-analysis2405-844010.1016/j.heliyon.2021.e08338https://doaj.org/article/4a94f31cc23943c39a86f8ecda0bad202021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2405844021024415https://doaj.org/toc/2405-8440Background: Treatment for polycystic ovary syndrome (PCOS) usually initiates with a series of lifestyle modifications such as diet, weight loss, and exercise. Aims: We, therefore, conducted this meta-analysis to systematically review and evaluate the possible benefits of LGD on a range of anthropometric, clinical, and biochemical parameters in women with PCOS. Methods: We performed a systematic search through major indexing databases, including Scopus, Pubmed/Medline, ISI web of science, Embase, Cochrane central, and CINAHL (1966–April 30, 2021) using key concepts of PCOS. Results: Of 935 initial publications, 542 remain after duplicates removal. Then, 141 records were removed at the title and abstract screening level. After excluding 392 literatures, we finally included 8 articles. The final selected studies included 412 overweight and obese individuals with PCOS (207 cases in LGID group and 205 patients in comparators) with a mean age of 21–32 years. Measured emotional health (3 studies, 132 participants, SMD: -1.97; 95%CI:-3.54, -0.40, P = 0.01, I2 = 89%) and body hair (3 studies, 132 participants, SMD: -0.40; 95%CI:-0.46, -0.35, P < 0.0001, I2 = 0%), were found to be significantly lower in women in LGD vs control diet groups. Moreover, infertility (3 studies, 132 participants, SMD: 1.45; 95%CI: 0.30, 2.61, P = 0.01, I2 = 79%) was significantly higher in women in LGD vs control diet groups. Conclusion: The present meta-analysis has shown that LGD may play a significant role in reducing the risk and improving the clinical and biochemical features of PCOS. So far the evidences for choosing the best dietary modalities for PCOS are not strong to make a definite recommendation.Najmieh SaadatiFatemeh HaidariMojgan BaratiRoshan NikbakhtGolshan MirmomeniFakher RahimElsevierarticleGlycemic indexLow-GI dietsEndocrine parametersBlood lipidsPCOSQ domainsScience (General)Q1-390Social sciences (General)H1-99ENHeliyon, Vol 7, Iss 11, Pp e08338- (2021)
institution DOAJ
collection DOAJ
language EN
topic Glycemic index
Low-GI diets
Endocrine parameters
Blood lipids
PCOSQ domains
Science (General)
Q1-390
Social sciences (General)
H1-99
spellingShingle Glycemic index
Low-GI diets
Endocrine parameters
Blood lipids
PCOSQ domains
Science (General)
Q1-390
Social sciences (General)
H1-99
Najmieh Saadati
Fatemeh Haidari
Mojgan Barati
Roshan Nikbakht
Golshan Mirmomeni
Fakher Rahim
The effect of low glycemic index diet on the reproductive and clinical profile in women with polycystic ovarian syndrome: A systematic review and meta-analysis
description Background: Treatment for polycystic ovary syndrome (PCOS) usually initiates with a series of lifestyle modifications such as diet, weight loss, and exercise. Aims: We, therefore, conducted this meta-analysis to systematically review and evaluate the possible benefits of LGD on a range of anthropometric, clinical, and biochemical parameters in women with PCOS. Methods: We performed a systematic search through major indexing databases, including Scopus, Pubmed/Medline, ISI web of science, Embase, Cochrane central, and CINAHL (1966–April 30, 2021) using key concepts of PCOS. Results: Of 935 initial publications, 542 remain after duplicates removal. Then, 141 records were removed at the title and abstract screening level. After excluding 392 literatures, we finally included 8 articles. The final selected studies included 412 overweight and obese individuals with PCOS (207 cases in LGID group and 205 patients in comparators) with a mean age of 21–32 years. Measured emotional health (3 studies, 132 participants, SMD: -1.97; 95%CI:-3.54, -0.40, P = 0.01, I2 = 89%) and body hair (3 studies, 132 participants, SMD: -0.40; 95%CI:-0.46, -0.35, P < 0.0001, I2 = 0%), were found to be significantly lower in women in LGD vs control diet groups. Moreover, infertility (3 studies, 132 participants, SMD: 1.45; 95%CI: 0.30, 2.61, P = 0.01, I2 = 79%) was significantly higher in women in LGD vs control diet groups. Conclusion: The present meta-analysis has shown that LGD may play a significant role in reducing the risk and improving the clinical and biochemical features of PCOS. So far the evidences for choosing the best dietary modalities for PCOS are not strong to make a definite recommendation.
format article
author Najmieh Saadati
Fatemeh Haidari
Mojgan Barati
Roshan Nikbakht
Golshan Mirmomeni
Fakher Rahim
author_facet Najmieh Saadati
Fatemeh Haidari
Mojgan Barati
Roshan Nikbakht
Golshan Mirmomeni
Fakher Rahim
author_sort Najmieh Saadati
title The effect of low glycemic index diet on the reproductive and clinical profile in women with polycystic ovarian syndrome: A systematic review and meta-analysis
title_short The effect of low glycemic index diet on the reproductive and clinical profile in women with polycystic ovarian syndrome: A systematic review and meta-analysis
title_full The effect of low glycemic index diet on the reproductive and clinical profile in women with polycystic ovarian syndrome: A systematic review and meta-analysis
title_fullStr The effect of low glycemic index diet on the reproductive and clinical profile in women with polycystic ovarian syndrome: A systematic review and meta-analysis
title_full_unstemmed The effect of low glycemic index diet on the reproductive and clinical profile in women with polycystic ovarian syndrome: A systematic review and meta-analysis
title_sort effect of low glycemic index diet on the reproductive and clinical profile in women with polycystic ovarian syndrome: a systematic review and meta-analysis
publisher Elsevier
publishDate 2021
url https://doaj.org/article/4a94f31cc23943c39a86f8ecda0bad20
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