Massive withdrawal symptoms and affective vulnerability are associated with variants of the CHRNA4 gene in a subgroup of smokers.

Heterogeneous phenotypes of complex disorders pose a great challenge for genetic association studies and for the development of personalized treatment strategies. Cluster analysis of phenotypic data has been recently proposed as a reliable auxiliary method for such studies. A cohort of 236 treatment...

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Main Authors: Judit Lazary, Peter Dome, Iren Csala, Gabor Kovacs, Gabor Faludi, Mari Kaunisto, Balazs Dome
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
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Online Access:https://doaj.org/article/4a9712a0c2274ed0a52338071f2fdce8
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