MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins

Channelrhodopsins (ChRs) are algal light-gated ion channels used as optogenetic tools for manipulating neuronal activity. Here authors present a metagenomically identified family of phylogenetically distinct anion-conducting ChRs (MerMAIDs) which desensitize during continuous illumination due to acc...

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Autores principales:	Johannes Oppermann, Paul Fischer, Arita Silapetere, Bernhard Liepe, Silvia Rodriguez-Rozada, José Flores-Uribe, Enrico Peter, Anke Keidel, Johannes Vierock, Joel Kaufmann, Matthias Broser, Meike Luck, Franz Bartl, Peter Hildebrandt, J. Simon Wiegert, Oded Béjà, Peter Hegemann, Jonas Wietek
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4a9a09bdb29444b3a95997984a933cb5
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spelling	oai:doaj.org-article:4a9a09bdb29444b3a95997984a933cb52021-12-02T16:58:07ZMerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins10.1038/s41467-019-11322-62041-1723https://doaj.org/article/4a9a09bdb29444b3a95997984a933cb52019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11322-6https://doaj.org/toc/2041-1723Channelrhodopsins (ChRs) are algal light-gated ion channels used as optogenetic tools for manipulating neuronal activity. Here authors present a metagenomically identified family of phylogenetically distinct anion-conducting ChRs (MerMAIDs) which desensitize during continuous illumination due to accumulation of a non-conducting photointermediate.Johannes OppermannPaul FischerArita SilapetereBernhard LiepeSilvia Rodriguez-RozadaJosé Flores-UribeEnrico PeterAnke KeidelJohannes VierockJoel KaufmannMatthias BroserMeike LuckFranz BartlPeter HildebrandtJ. Simon WiegertOded BéjàPeter HegemannJonas WietekNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Johannes Oppermann Paul Fischer Arita Silapetere Bernhard Liepe Silvia Rodriguez-Rozada José Flores-Uribe Enrico Peter Anke Keidel Johannes Vierock Joel Kaufmann Matthias Broser Meike Luck Franz Bartl Peter Hildebrandt J. Simon Wiegert Oded Béjà Peter Hegemann Jonas Wietek MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins
description	Channelrhodopsins (ChRs) are algal light-gated ion channels used as optogenetic tools for manipulating neuronal activity. Here authors present a metagenomically identified family of phylogenetically distinct anion-conducting ChRs (MerMAIDs) which desensitize during continuous illumination due to accumulation of a non-conducting photointermediate.
format	article
author	Johannes Oppermann Paul Fischer Arita Silapetere Bernhard Liepe Silvia Rodriguez-Rozada José Flores-Uribe Enrico Peter Anke Keidel Johannes Vierock Joel Kaufmann Matthias Broser Meike Luck Franz Bartl Peter Hildebrandt J. Simon Wiegert Oded Béjà Peter Hegemann Jonas Wietek
author_facet	Johannes Oppermann Paul Fischer Arita Silapetere Bernhard Liepe Silvia Rodriguez-Rozada José Flores-Uribe Enrico Peter Anke Keidel Johannes Vierock Joel Kaufmann Matthias Broser Meike Luck Franz Bartl Peter Hildebrandt J. Simon Wiegert Oded Béjà Peter Hegemann Jonas Wietek
author_sort	Johannes Oppermann
title	MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins
title_short	MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins
title_full	MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins
title_fullStr	MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins
title_full_unstemmed	MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins
title_sort	mermaids: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/4a9a09bdb29444b3a95997984a933cb5
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MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins

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