ROR2 has a protective role in melanoma by inhibiting Akt activity, cell-cycle progression, and proliferation

Abstract Background Receptor tyrosine kinase-like orphan receptor 2 (ROR2) is a Wnt5a receptor aberrantly expressed in cancer that was shown to either suppress or promote carcinogenesis in different tumor types. Our goal was to study the role of ROR2 in melanoma. Methods Gain and loss-of-function st...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: María Victoria Castro, Gastón Alexis Barbero, María Belén Villanueva, Luca Grumolato, Jérémie Nsengimana, Julia Newton-Bishop, Edith Illescas, María Josefina Quezada, Pablo Lopez-Bergami
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
Akt
R
Acceso en línea:https://doaj.org/article/4aa18ad8bb6d4dfa887f300feb49a3f7
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares