Structural Characterization of Diazabicyclooctane β-Lactam “Enhancers” in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa
Antibiotic resistance is a significant clinical problem. Developing novel antibiotics that overcome known resistance mechanisms is highly desired.
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American Society for Microbiology
2021
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oai:doaj.org-article:4aa59e08d52045aea5cd17d19b97f5ff2021-11-03T18:15:38ZStructural Characterization of Diazabicyclooctane β-Lactam “Enhancers” in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa2161-21292150-751110.1128/mBio.03058-20https://doaj.org/article/4aa59e08d52045aea5cd17d19b97f5ff2021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03058-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 Antibiotic resistance is a significant clinical problem. Developing novel antibiotics that overcome known resistance mechanisms is highly desired.Malligarjunan RajavelVijay KumarHa NguyenJacob WyattSteven H. MarshallKrisztina M. Papp-WallacePrasad DeshpandeSatish BhavsarRavindra YeoleSachin BhagwatMahesh PatelRobert A. BonomoFocco van den AkkerAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Microbiology QR1-502 |
| spellingShingle |
Microbiology QR1-502 Malligarjunan Rajavel Vijay Kumar Ha Nguyen Jacob Wyatt Steven H. Marshall Krisztina M. Papp-Wallace Prasad Deshpande Satish Bhavsar Ravindra Yeole Sachin Bhagwat Mahesh Patel Robert A. Bonomo Focco van den Akker Structural Characterization of Diazabicyclooctane β-Lactam “Enhancers” in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa |
| description |
Antibiotic resistance is a significant clinical problem. Developing novel antibiotics that overcome known resistance mechanisms is highly desired. |
| format |
article |
| author |
Malligarjunan Rajavel Vijay Kumar Ha Nguyen Jacob Wyatt Steven H. Marshall Krisztina M. Papp-Wallace Prasad Deshpande Satish Bhavsar Ravindra Yeole Sachin Bhagwat Mahesh Patel Robert A. Bonomo Focco van den Akker |
| author_facet |
Malligarjunan Rajavel Vijay Kumar Ha Nguyen Jacob Wyatt Steven H. Marshall Krisztina M. Papp-Wallace Prasad Deshpande Satish Bhavsar Ravindra Yeole Sachin Bhagwat Mahesh Patel Robert A. Bonomo Focco van den Akker |
| author_sort |
Malligarjunan Rajavel |
| title |
Structural Characterization of Diazabicyclooctane β-Lactam “Enhancers” in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa |
| title_short |
Structural Characterization of Diazabicyclooctane β-Lactam “Enhancers” in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa |
| title_full |
Structural Characterization of Diazabicyclooctane β-Lactam “Enhancers” in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa |
| title_fullStr |
Structural Characterization of Diazabicyclooctane β-Lactam “Enhancers” in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa |
| title_full_unstemmed |
Structural Characterization of Diazabicyclooctane β-Lactam “Enhancers” in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa |
| title_sort |
structural characterization of diazabicyclooctane β-lactam “enhancers” in complex with penicillin-binding proteins pbp2 and pbp3 of pseudomonas aeruginosa |
| publisher |
American Society for Microbiology |
| publishDate |
2021 |
| url |
https://doaj.org/article/4aa59e08d52045aea5cd17d19b97f5ff |
| work_keys_str_mv |
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| _version_ |
1718445454328332288 |