Oxytocin Receptor Gene Polymorphism in Lactating Dogs

Genetic variations in the oxytocinergic system, known to regulate social behavior throughout the evolution of mammals, are believed to account for differences in mammalian social behavior. Particularly, polymorphic variants of the oxytocin receptor (<i>OXTR</i>) gene have been associated...

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Autores principales:	Asahi Ogi, Valentina Naef, Filippo Maria Santorelli, Chiara Mariti, Angelo Gazzano
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	behavior dog gene maternal care oxytocin polymorphism Veterinary medicine SF600-1100 Zoology QL1-991
Acceso en línea:	https://doaj.org/article/4aa7ebb9f7cf444091d431a1da233044
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spelling	oai:doaj.org-article:4aa7ebb9f7cf444091d431a1da2330442021-11-25T16:15:18ZOxytocin Receptor Gene Polymorphism in Lactating Dogs10.3390/ani111130992076-2615https://doaj.org/article/4aa7ebb9f7cf444091d431a1da2330442021-10-01T00:00:00Zhttps://www.mdpi.com/2076-2615/11/11/3099https://doaj.org/toc/2076-2615Genetic variations in the oxytocinergic system, known to regulate social behavior throughout the evolution of mammals, are believed to account for differences in mammalian social behavior. Particularly, polymorphic variants of the oxytocin receptor (<i>OXTR</i>) gene have been associated with behavioral variations in both humans and dogs. In this study, we offered evidence of the correlation between levels of salivary oxytocin (sOXT), maternal behavior and a single-nucleotide gene variant in <i>OXTR</i> (<i>rs</i>8679684) in nineteen lactating Labrador Retriever dogs. Carriers of at least one copy of the minor A allele showed higher levels of sOXT and maternal care in comparison with the homozygous T allele carriers. Considering the relevance of mother care in newborn development, these findings could help us to better understand the possible impact of variants in the <i>OXTR</i> gene in selecting dams.Asahi OgiValentina NaefFilippo Maria SantorelliChiara MaritiAngelo GazzanoMDPI AGarticlebehaviordoggenematernal careoxytocinpolymorphismVeterinary medicineSF600-1100ZoologyQL1-991ENAnimals, Vol 11, Iss 3099, p 3099 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	behavior dog gene maternal care oxytocin polymorphism Veterinary medicine SF600-1100 Zoology QL1-991
spellingShingle	behavior dog gene maternal care oxytocin polymorphism Veterinary medicine SF600-1100 Zoology QL1-991 Asahi Ogi Valentina Naef Filippo Maria Santorelli Chiara Mariti Angelo Gazzano Oxytocin Receptor Gene Polymorphism in Lactating Dogs
description	Genetic variations in the oxytocinergic system, known to regulate social behavior throughout the evolution of mammals, are believed to account for differences in mammalian social behavior. Particularly, polymorphic variants of the oxytocin receptor (<i>OXTR</i>) gene have been associated with behavioral variations in both humans and dogs. In this study, we offered evidence of the correlation between levels of salivary oxytocin (sOXT), maternal behavior and a single-nucleotide gene variant in <i>OXTR</i> (<i>rs</i>8679684) in nineteen lactating Labrador Retriever dogs. Carriers of at least one copy of the minor A allele showed higher levels of sOXT and maternal care in comparison with the homozygous T allele carriers. Considering the relevance of mother care in newborn development, these findings could help us to better understand the possible impact of variants in the <i>OXTR</i> gene in selecting dams.
format	article
author	Asahi Ogi Valentina Naef Filippo Maria Santorelli Chiara Mariti Angelo Gazzano
author_facet	Asahi Ogi Valentina Naef Filippo Maria Santorelli Chiara Mariti Angelo Gazzano
author_sort	Asahi Ogi
title	Oxytocin Receptor Gene Polymorphism in Lactating Dogs
title_short	Oxytocin Receptor Gene Polymorphism in Lactating Dogs
title_full	Oxytocin Receptor Gene Polymorphism in Lactating Dogs
title_fullStr	Oxytocin Receptor Gene Polymorphism in Lactating Dogs
title_full_unstemmed	Oxytocin Receptor Gene Polymorphism in Lactating Dogs
title_sort	oxytocin receptor gene polymorphism in lactating dogs
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/4aa7ebb9f7cf444091d431a1da233044
work_keys_str_mv	AT asahiogi oxytocinreceptorgenepolymorphisminlactatingdogs AT valentinanaef oxytocinreceptorgenepolymorphisminlactatingdogs AT filippomariasantorelli oxytocinreceptorgenepolymorphisminlactatingdogs AT chiaramariti oxytocinreceptorgenepolymorphisminlactatingdogs AT angelogazzano oxytocinreceptorgenepolymorphisminlactatingdogs
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Oxytocin Receptor Gene Polymorphism in Lactating Dogs

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