Guided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial.

<h4>Background</h4>Access to Cognitive behavioural therapy (CBT) for depression is limited. One solution is CBT self-help books. Trial Objectives: To assess the impact of a guided self-help CBT book (GSH-CBT) on mood, compared to treatment as usual (TAU).<h4>Hypotheses</h4>GS...

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Autores principales:	Christopher Williams, Philip Wilson, Jill Morrison, Alex McMahon, Andrew Walker, Lesley Allan, Alex McConnachie, Yvonne McNeill, Louise Tansey
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4aa97ee314e14f9c9cdb0917e5ad6a15
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spelling	oai:doaj.org-article:4aa97ee314e14f9c9cdb0917e5ad6a152021-11-18T08:01:53ZGuided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial.1932-620310.1371/journal.pone.0052735https://doaj.org/article/4aa97ee314e14f9c9cdb0917e5ad6a152013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23326352/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Access to Cognitive behavioural therapy (CBT) for depression is limited. One solution is CBT self-help books. Trial Objectives: To assess the impact of a guided self-help CBT book (GSH-CBT) on mood, compared to treatment as usual (TAU).<h4>Hypotheses</h4>GSH-CBT will have improved mood and knowledge of the causes and treatment of depression compared to the control receiving TAUGuided self-help will be acceptable to patients and staff.<h4>Methods and findings</h4><h4>Participants</h4>Adults attending seven general practices in Glasgow, UK with a BDI-II score of ≥14. 141 randomised to GSH-CBT and 140 to TAU.<h4>Interventions</h4>RCT comparing 'Overcoming Depression: A Five Areas Approach' book plus 3-4 short face to face support appointments totalling up to 2 hours of guided support, compared with general practitioner TAU.<h4>Primary outcome</h4>The BDI (II) score at 4 months. Numbers analysed: 281 at baseline, 203 at 4 months (primary outcome), 117 at 12 months.<h4>Outcome</h4>Mean BDI-II scores were lower in the GSH-CBT group at 4 months by 5.3 points (2.6 to 7.9, p<0.001). At 4 and 12 months there were also significantly higher proportions of participants achieving a 50% reduction in BDI-II in the GSH-CBT arm. The mean support was 2 sessions with 42.7 minutes for session 1, 41.4 minutes for session 2 and 40.2 minutes of support for session 3. Adverse effects/Harms: Significantly less deterioration in mood in GSH-CBT (2.0% compared to 9.8% in the TAU group for BDI-II category change).<h4>Limitations</h4>Weaknesses: Our follow-up rate of 72.2% at 4 months is better than predicted but is poorer at 12 months (41.6%). In the GSH-CBT arm, around 50% of people attended 2 or fewer sessions. 22% failed to take up treatment.<h4>Conclusions</h4>GSH-CBT is substantially more effective than TAU.<h4>Trial registration</h4>Controlled-Trials.com ISRCTN13475030.Christopher WilliamsPhilip WilsonJill MorrisonAlex McMahonAndrew WalkerLesley AllanAlex McConnachieYvonne McNeillLouise TanseyPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 1, p e52735 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Christopher Williams Philip Wilson Jill Morrison Alex McMahon Andrew Walker Lesley Allan Alex McConnachie Yvonne McNeill Louise Tansey Guided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial.
description	<h4>Background</h4>Access to Cognitive behavioural therapy (CBT) for depression is limited. One solution is CBT self-help books. Trial Objectives: To assess the impact of a guided self-help CBT book (GSH-CBT) on mood, compared to treatment as usual (TAU).<h4>Hypotheses</h4>GSH-CBT will have improved mood and knowledge of the causes and treatment of depression compared to the control receiving TAUGuided self-help will be acceptable to patients and staff.<h4>Methods and findings</h4><h4>Participants</h4>Adults attending seven general practices in Glasgow, UK with a BDI-II score of ≥14. 141 randomised to GSH-CBT and 140 to TAU.<h4>Interventions</h4>RCT comparing 'Overcoming Depression: A Five Areas Approach' book plus 3-4 short face to face support appointments totalling up to 2 hours of guided support, compared with general practitioner TAU.<h4>Primary outcome</h4>The BDI (II) score at 4 months. Numbers analysed: 281 at baseline, 203 at 4 months (primary outcome), 117 at 12 months.<h4>Outcome</h4>Mean BDI-II scores were lower in the GSH-CBT group at 4 months by 5.3 points (2.6 to 7.9, p<0.001). At 4 and 12 months there were also significantly higher proportions of participants achieving a 50% reduction in BDI-II in the GSH-CBT arm. The mean support was 2 sessions with 42.7 minutes for session 1, 41.4 minutes for session 2 and 40.2 minutes of support for session 3. Adverse effects/Harms: Significantly less deterioration in mood in GSH-CBT (2.0% compared to 9.8% in the TAU group for BDI-II category change).<h4>Limitations</h4>Weaknesses: Our follow-up rate of 72.2% at 4 months is better than predicted but is poorer at 12 months (41.6%). In the GSH-CBT arm, around 50% of people attended 2 or fewer sessions. 22% failed to take up treatment.<h4>Conclusions</h4>GSH-CBT is substantially more effective than TAU.<h4>Trial registration</h4>Controlled-Trials.com ISRCTN13475030.
format	article
author	Christopher Williams Philip Wilson Jill Morrison Alex McMahon Andrew Walker Lesley Allan Alex McConnachie Yvonne McNeill Louise Tansey
author_facet	Christopher Williams Philip Wilson Jill Morrison Alex McMahon Andrew Walker Lesley Allan Alex McConnachie Yvonne McNeill Louise Tansey
author_sort	Christopher Williams
title	Guided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial.
title_short	Guided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial.
title_full	Guided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial.
title_fullStr	Guided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial.
title_full_unstemmed	Guided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial.
title_sort	guided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/4aa97ee314e14f9c9cdb0917e5ad6a15
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Guided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial.

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