A minimalist approach to stereoselective glycosylation with unprotected donors

Oligosaccharide synthesis is encumbered by multiple protection and deprotection steps. Here, the authors report a protection-free yet stereoselective and regioselective glycosylation strategy using boron-masked glycosyl donors, and demonstrate efficient synthesis of oligosaccharides over a wide subs...

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Autores principales:	Kim Le Mai Hoang, Jing-xi He, Gábor Báti, Mary B. Chan-Park, Xue-Wei Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4ab338a2004a4e7baeacab2ce5d571dc
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spelling	oai:doaj.org-article:4ab338a2004a4e7baeacab2ce5d571dc2021-12-02T14:42:37ZA minimalist approach to stereoselective glycosylation with unprotected donors10.1038/s41467-017-01073-72041-1723https://doaj.org/article/4ab338a2004a4e7baeacab2ce5d571dc2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01073-7https://doaj.org/toc/2041-1723Oligosaccharide synthesis is encumbered by multiple protection and deprotection steps. Here, the authors report a protection-free yet stereoselective and regioselective glycosylation strategy using boron-masked glycosyl donors, and demonstrate efficient synthesis of oligosaccharides over a wide substrate scope.Kim Le Mai HoangJing-xi HeGábor BátiMary B. Chan-ParkXue-Wei LiuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kim Le Mai Hoang Jing-xi He Gábor Báti Mary B. Chan-Park Xue-Wei Liu A minimalist approach to stereoselective glycosylation with unprotected donors
description	Oligosaccharide synthesis is encumbered by multiple protection and deprotection steps. Here, the authors report a protection-free yet stereoselective and regioselective glycosylation strategy using boron-masked glycosyl donors, and demonstrate efficient synthesis of oligosaccharides over a wide substrate scope.
format	article
author	Kim Le Mai Hoang Jing-xi He Gábor Báti Mary B. Chan-Park Xue-Wei Liu
author_facet	Kim Le Mai Hoang Jing-xi He Gábor Báti Mary B. Chan-Park Xue-Wei Liu
author_sort	Kim Le Mai Hoang
title	A minimalist approach to stereoselective glycosylation with unprotected donors
title_short	A minimalist approach to stereoselective glycosylation with unprotected donors
title_full	A minimalist approach to stereoselective glycosylation with unprotected donors
title_fullStr	A minimalist approach to stereoselective glycosylation with unprotected donors
title_full_unstemmed	A minimalist approach to stereoselective glycosylation with unprotected donors
title_sort	minimalist approach to stereoselective glycosylation with unprotected donors
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/4ab338a2004a4e7baeacab2ce5d571dc
work_keys_str_mv	AT kimlemaihoang aminimalistapproachtostereoselectiveglycosylationwithunprotecteddonors AT jingxihe aminimalistapproachtostereoselectiveglycosylationwithunprotecteddonors AT gaborbati aminimalistapproachtostereoselectiveglycosylationwithunprotecteddonors AT marybchanpark aminimalistapproachtostereoselectiveglycosylationwithunprotecteddonors AT xueweiliu aminimalistapproachtostereoselectiveglycosylationwithunprotecteddonors AT kimlemaihoang minimalistapproachtostereoselectiveglycosylationwithunprotecteddonors AT jingxihe minimalistapproachtostereoselectiveglycosylationwithunprotecteddonors AT gaborbati minimalistapproachtostereoselectiveglycosylationwithunprotecteddonors AT marybchanpark minimalistapproachtostereoselectiveglycosylationwithunprotecteddonors AT xueweiliu minimalistapproachtostereoselectiveglycosylationwithunprotecteddonors
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A minimalist approach to stereoselective glycosylation with unprotected donors

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