Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study
Objective. The present study aimed to evaluate the lipid profile and atherogenic indexes in HIV-positive women with and without coinfection with human papillomavirus. Methods. Preliminary study was conducted with HIV-positive women. Laboratory tests (lipid profile, glycid profile, and atherogenic in...
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Hindawi Limited
2021
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oai:doaj.org-article:4ab440ab09d24c8da1b4458290abe59f2021-11-15T01:19:55ZPrevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study2090-908X10.1155/2021/4318423https://doaj.org/article/4ab440ab09d24c8da1b4458290abe59f2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/4318423https://doaj.org/toc/2090-908XObjective. The present study aimed to evaluate the lipid profile and atherogenic indexes in HIV-positive women with and without coinfection with human papillomavirus. Methods. Preliminary study was conducted with HIV-positive women. Laboratory tests (lipid profile, glycid profile, and atherogenic indexes) and detection of human papillomavirus (nested PCR technique using PGMY 09 and 11 primers, GP+5, and GP+6) were performed. For the analysis of the results, the data were categorized into two groups: with coinfection (HIV+/HPV+) and without coinfection (HIV+/HPV–). Results. Eighty-two HIV-positive women, aged between 35 and 49 years, participated in this study among whom 50% had HPV coinfection (HIV+/HPV+). Regarding comorbidities, there was a predominance of dyslipidemia (46.3%). The analysis of laboratory determinations and atherogenic indexes showed statistical relevance in the serum concentrations of total cholesterol (p=0.04), LDL cholesterol (p=0.03), and non-HDL cholesterol (p=0.04), as well as for the Castelli I index, Castelli II index, and atherogenic coefficient (p=0.04, 0.04, and 0.03, respectively). Conclusion. The present study demonstrated a correlation between the lipid profile and atherogenic indexes with HIV/HPV coinfection, demonstrating a possible synergy between these viruses. However, further studies in this area must be carried out.Mônika Machado de CarvalhoKarina Donato FookMaria José Abigail Mendes AraújoSulayne Janayna Araújo GuimarãesCamila Penha Abreu SouzaCarla Déa Trindade BarbosaAna Cléa Cutrim Diniz de MoraisAlessandra Costa de Sales MunizDeborah Rocha de AraújoMaria Fernanda Bezerra Lima BertolacciniIlka Kassandra Pereira BelfortMarcelo de Souza AndradeSally Cristina Moutinho MonteiroHindawi LimitedarticleMedicineRScienceQENScientifica, Vol 2021 (2021) |
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Medicine R Science Q |
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Medicine R Science Q Mônika Machado de Carvalho Karina Donato Fook Maria José Abigail Mendes Araújo Sulayne Janayna Araújo Guimarães Camila Penha Abreu Souza Carla Déa Trindade Barbosa Ana Cléa Cutrim Diniz de Morais Alessandra Costa de Sales Muniz Deborah Rocha de Araújo Maria Fernanda Bezerra Lima Bertolaccini Ilka Kassandra Pereira Belfort Marcelo de Souza Andrade Sally Cristina Moutinho Monteiro Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study |
| description |
Objective. The present study aimed to evaluate the lipid profile and atherogenic indexes in HIV-positive women with and without coinfection with human papillomavirus. Methods. Preliminary study was conducted with HIV-positive women. Laboratory tests (lipid profile, glycid profile, and atherogenic indexes) and detection of human papillomavirus (nested PCR technique using PGMY 09 and 11 primers, GP+5, and GP+6) were performed. For the analysis of the results, the data were categorized into two groups: with coinfection (HIV+/HPV+) and without coinfection (HIV+/HPV–). Results. Eighty-two HIV-positive women, aged between 35 and 49 years, participated in this study among whom 50% had HPV coinfection (HIV+/HPV+). Regarding comorbidities, there was a predominance of dyslipidemia (46.3%). The analysis of laboratory determinations and atherogenic indexes showed statistical relevance in the serum concentrations of total cholesterol (p=0.04), LDL cholesterol (p=0.03), and non-HDL cholesterol (p=0.04), as well as for the Castelli I index, Castelli II index, and atherogenic coefficient (p=0.04, 0.04, and 0.03, respectively). Conclusion. The present study demonstrated a correlation between the lipid profile and atherogenic indexes with HIV/HPV coinfection, demonstrating a possible synergy between these viruses. However, further studies in this area must be carried out. |
| format |
article |
| author |
Mônika Machado de Carvalho Karina Donato Fook Maria José Abigail Mendes Araújo Sulayne Janayna Araújo Guimarães Camila Penha Abreu Souza Carla Déa Trindade Barbosa Ana Cléa Cutrim Diniz de Morais Alessandra Costa de Sales Muniz Deborah Rocha de Araújo Maria Fernanda Bezerra Lima Bertolaccini Ilka Kassandra Pereira Belfort Marcelo de Souza Andrade Sally Cristina Moutinho Monteiro |
| author_facet |
Mônika Machado de Carvalho Karina Donato Fook Maria José Abigail Mendes Araújo Sulayne Janayna Araújo Guimarães Camila Penha Abreu Souza Carla Déa Trindade Barbosa Ana Cléa Cutrim Diniz de Morais Alessandra Costa de Sales Muniz Deborah Rocha de Araújo Maria Fernanda Bezerra Lima Bertolaccini Ilka Kassandra Pereira Belfort Marcelo de Souza Andrade Sally Cristina Moutinho Monteiro |
| author_sort |
Mônika Machado de Carvalho |
| title |
Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study |
| title_short |
Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study |
| title_full |
Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study |
| title_fullStr |
Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study |
| title_full_unstemmed |
Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study |
| title_sort |
prevalence of dyslipidemia in hiv-positive women with hpv coinfection: a preliminary study |
| publisher |
Hindawi Limited |
| publishDate |
2021 |
| url |
https://doaj.org/article/4ab440ab09d24c8da1b4458290abe59f |
| work_keys_str_mv |
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