Influenza colloidal gold method and blood routine tests combination for rapid diagnosis of influenza: a decision tree-based analysis

Abstract Rapid influenza diagnosis can facilitate targeted treatment and reduce antibiotic misuse. However, diagnosis efficacy remains unclear. This study examined the efficacy of a colloidal gold rapid test for rapid influenza diagnosis. Clinical characteristics of 520 patients with influenza-like...

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Autores principales:	Xiaoguang Li, Jing Chen, Fei Lin, Wei Wang, Jie Xu, Nan Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Diseases of the respiratory system RC705-779
Acceso en línea:	https://doaj.org/article/4abcc27232674f84af692c6694210794
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spelling	oai:doaj.org-article:4abcc27232674f84af692c66942107942021-12-02T15:32:56ZInfluenza colloidal gold method and blood routine tests combination for rapid diagnosis of influenza: a decision tree-based analysis10.1038/s41533-021-00251-x2055-1010https://doaj.org/article/4abcc27232674f84af692c66942107942021-07-01T00:00:00Zhttps://doi.org/10.1038/s41533-021-00251-xhttps://doaj.org/toc/2055-1010Abstract Rapid influenza diagnosis can facilitate targeted treatment and reduce antibiotic misuse. However, diagnosis efficacy remains unclear. This study examined the efficacy of a colloidal gold rapid test for rapid influenza diagnosis. Clinical characteristics of 520 patients with influenza-like illness presenting at a fever outpatient clinic during two influenza seasons (2017–2018; 2018–2019) were evaluated. The clinical manifestations and results of routine blood, colloidal gold, and nucleic acid tests were used to construct a decision tree with three layers, nine nodes, and five terminal nodes. The combined positive predictive value of a positive colloidal gold test result and monocyte level within 10.95–12.55% was 88.2%. The combined negative predictive value of a negative colloidal gold test result and white blood cell count > 9.075 × 109/L was 84.9%. The decision-tree model showed the satisfactory accuracy of an early influenza diagnosis based on colloidal gold and routine blood test results.Xiaoguang LiJing ChenFei LinWei WangJie XuNan LiNature PortfolioarticleDiseases of the respiratory systemRC705-779ENnpj Primary Care Respiratory Medicine, Vol 31, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the respiratory system RC705-779
spellingShingle	Diseases of the respiratory system RC705-779 Xiaoguang Li Jing Chen Fei Lin Wei Wang Jie Xu Nan Li Influenza colloidal gold method and blood routine tests combination for rapid diagnosis of influenza: a decision tree-based analysis
description	Abstract Rapid influenza diagnosis can facilitate targeted treatment and reduce antibiotic misuse. However, diagnosis efficacy remains unclear. This study examined the efficacy of a colloidal gold rapid test for rapid influenza diagnosis. Clinical characteristics of 520 patients with influenza-like illness presenting at a fever outpatient clinic during two influenza seasons (2017–2018; 2018–2019) were evaluated. The clinical manifestations and results of routine blood, colloidal gold, and nucleic acid tests were used to construct a decision tree with three layers, nine nodes, and five terminal nodes. The combined positive predictive value of a positive colloidal gold test result and monocyte level within 10.95–12.55% was 88.2%. The combined negative predictive value of a negative colloidal gold test result and white blood cell count > 9.075 × 109/L was 84.9%. The decision-tree model showed the satisfactory accuracy of an early influenza diagnosis based on colloidal gold and routine blood test results.
format	article
author	Xiaoguang Li Jing Chen Fei Lin Wei Wang Jie Xu Nan Li
author_facet	Xiaoguang Li Jing Chen Fei Lin Wei Wang Jie Xu Nan Li
author_sort	Xiaoguang Li
title	Influenza colloidal gold method and blood routine tests combination for rapid diagnosis of influenza: a decision tree-based analysis
title_short	Influenza colloidal gold method and blood routine tests combination for rapid diagnosis of influenza: a decision tree-based analysis
title_full	Influenza colloidal gold method and blood routine tests combination for rapid diagnosis of influenza: a decision tree-based analysis
title_fullStr	Influenza colloidal gold method and blood routine tests combination for rapid diagnosis of influenza: a decision tree-based analysis
title_full_unstemmed	Influenza colloidal gold method and blood routine tests combination for rapid diagnosis of influenza: a decision tree-based analysis
title_sort	influenza colloidal gold method and blood routine tests combination for rapid diagnosis of influenza: a decision tree-based analysis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4abcc27232674f84af692c6694210794
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Influenza colloidal gold method and blood routine tests combination for rapid diagnosis of influenza: a decision tree-based analysis

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