Evaluation of pre-chemotherapy antiemetic prescriptions in a hospital unit

Introduction: Antineoplastic drugs, due to their high toxicity, can lead to adverse reactions to drugs, such as emesis, which causes discomfort to the patient. These drugs can be classified according to emetogenic potential and have appropriate treatment protocols. Objectives: The aim of this study...

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Autores principales:	Andressa B. Souza, Benedito C. Cordeiro
Formato:	article
Lenguaje:	EN PT
Publicado:	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde 2020
Materias:	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/4ad41c443e9d4a05ac126490b7131984
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spelling	oai:doaj.org-article:4ad41c443e9d4a05ac126490b71319842021-11-28T02:45:34ZEvaluation of pre-chemotherapy antiemetic prescriptions in a hospital unit10.30968/rbfhss.2019.103.03412179-59242316-7750https://doaj.org/article/4ad41c443e9d4a05ac126490b71319842020-03-01T00:00:00Zhttps://www.rbfhss.org.br/sbrafh/article/view/341https://doaj.org/toc/2179-5924https://doaj.org/toc/2316-7750 Introduction: Antineoplastic drugs, due to their high toxicity, can lead to adverse reactions to drugs, such as emesis, which causes discomfort to the patient. These drugs can be classified according to emetogenic potential and have appropriate treatment protocols. Objectives: The aim of this study is to evaluate whether there is compliance between antiemetic prescription in patients receiving antineoplastic treatment in a hospital unit, according to pre-established emesis prevention protocols. Methods: This is a cross-sectional retrospective study of chemotherapy prescriptions analysis from January to April 2017. Data were analyzed according to the National Comprehensive Cancer Network 2017 Acute Emesis Prevention Protocol. Nonconformities were classified in: wrong medicine; wrong dose; wrong administration frequency and wrong administration route. Results: Of the 919 prescriptions analyzed, 83% did not comply with the protocol. The most common nonconformity found in the study was the wrong dose with the most prevalent scenario being the dexamethasone dose above the required dose. Conclusion: Most of the prescriptions analyzed did not comply with the pre-established protocol. This increases the likelihood of adverse drug reactions, does not effectively prevent emesis, thereby increasing patient weakness, decreasing quality of life, and wasting resources. Andressa B. SouzaBenedito C. CordeiroSociedade Brasileira de Farmácia Hospitalar e Serviços de SaúdearticlePublic aspects of medicineRA1-1270Pharmacy and materia medicaRS1-441Therapeutics. PharmacologyRM1-950ENPTRevista Brasileira de Farmácia Hospitalar e Serviços de Saúde, Vol 10, Iss 3 (2020)
institution	DOAJ
collection	DOAJ
language	EN PT
topic	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
spellingShingle	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950 Andressa B. Souza Benedito C. Cordeiro Evaluation of pre-chemotherapy antiemetic prescriptions in a hospital unit
description	Introduction: Antineoplastic drugs, due to their high toxicity, can lead to adverse reactions to drugs, such as emesis, which causes discomfort to the patient. These drugs can be classified according to emetogenic potential and have appropriate treatment protocols. Objectives: The aim of this study is to evaluate whether there is compliance between antiemetic prescription in patients receiving antineoplastic treatment in a hospital unit, according to pre-established emesis prevention protocols. Methods: This is a cross-sectional retrospective study of chemotherapy prescriptions analysis from January to April 2017. Data were analyzed according to the National Comprehensive Cancer Network 2017 Acute Emesis Prevention Protocol. Nonconformities were classified in: wrong medicine; wrong dose; wrong administration frequency and wrong administration route. Results: Of the 919 prescriptions analyzed, 83% did not comply with the protocol. The most common nonconformity found in the study was the wrong dose with the most prevalent scenario being the dexamethasone dose above the required dose. Conclusion: Most of the prescriptions analyzed did not comply with the pre-established protocol. This increases the likelihood of adverse drug reactions, does not effectively prevent emesis, thereby increasing patient weakness, decreasing quality of life, and wasting resources.
format	article
author	Andressa B. Souza Benedito C. Cordeiro
author_facet	Andressa B. Souza Benedito C. Cordeiro
author_sort	Andressa B. Souza
title	Evaluation of pre-chemotherapy antiemetic prescriptions in a hospital unit
title_short	Evaluation of pre-chemotherapy antiemetic prescriptions in a hospital unit
title_full	Evaluation of pre-chemotherapy antiemetic prescriptions in a hospital unit
title_fullStr	Evaluation of pre-chemotherapy antiemetic prescriptions in a hospital unit
title_full_unstemmed	Evaluation of pre-chemotherapy antiemetic prescriptions in a hospital unit
title_sort	evaluation of pre-chemotherapy antiemetic prescriptions in a hospital unit
publisher	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde
publishDate	2020
url	https://doaj.org/article/4ad41c443e9d4a05ac126490b7131984
work_keys_str_mv	AT andressabsouza evaluationofprechemotherapyantiemeticprescriptionsinahospitalunit AT beneditoccordeiro evaluationofprechemotherapyantiemeticprescriptionsinahospitalunit
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Evaluation of pre-chemotherapy antiemetic prescriptions in a hospital unit

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