A microRNA-initiated DNAzyme motor operating in living cells

Synthetic DNA nanomachines have been designed to perform a variety of tasksin vitro. Here, the authors build a nanomotor system that integrates a DNAzyme and DNA track on a gold nanoparticle, to facilitate cellular uptake, and apply it as a real-time miRNA imaging tool in living cells.

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Autores principales:	Hanyong Peng, Xing-Fang Li, Hongquan Zhang, X. Chris Le
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4ad92c16044b447dae1c9aea8fcaf741
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id	oai:doaj.org-article:4ad92c16044b447dae1c9aea8fcaf741
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spelling	oai:doaj.org-article:4ad92c16044b447dae1c9aea8fcaf7412021-12-02T14:41:18ZA microRNA-initiated DNAzyme motor operating in living cells10.1038/ncomms143782041-1723https://doaj.org/article/4ad92c16044b447dae1c9aea8fcaf7412017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14378https://doaj.org/toc/2041-1723Synthetic DNA nanomachines have been designed to perform a variety of tasksin vitro. Here, the authors build a nanomotor system that integrates a DNAzyme and DNA track on a gold nanoparticle, to facilitate cellular uptake, and apply it as a real-time miRNA imaging tool in living cells.Hanyong PengXing-Fang LiHongquan ZhangX. Chris LeNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hanyong Peng Xing-Fang Li Hongquan Zhang X. Chris Le A microRNA-initiated DNAzyme motor operating in living cells
description	Synthetic DNA nanomachines have been designed to perform a variety of tasksin vitro. Here, the authors build a nanomotor system that integrates a DNAzyme and DNA track on a gold nanoparticle, to facilitate cellular uptake, and apply it as a real-time miRNA imaging tool in living cells.
format	article
author	Hanyong Peng Xing-Fang Li Hongquan Zhang X. Chris Le
author_facet	Hanyong Peng Xing-Fang Li Hongquan Zhang X. Chris Le
author_sort	Hanyong Peng
title	A microRNA-initiated DNAzyme motor operating in living cells
title_short	A microRNA-initiated DNAzyme motor operating in living cells
title_full	A microRNA-initiated DNAzyme motor operating in living cells
title_fullStr	A microRNA-initiated DNAzyme motor operating in living cells
title_full_unstemmed	A microRNA-initiated DNAzyme motor operating in living cells
title_sort	microrna-initiated dnazyme motor operating in living cells
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/4ad92c16044b447dae1c9aea8fcaf741
work_keys_str_mv	AT hanyongpeng amicrornainitiateddnazymemotoroperatinginlivingcells AT xingfangli amicrornainitiateddnazymemotoroperatinginlivingcells AT hongquanzhang amicrornainitiateddnazymemotoroperatinginlivingcells AT xchrisle amicrornainitiateddnazymemotoroperatinginlivingcells AT hanyongpeng micrornainitiateddnazymemotoroperatinginlivingcells AT xingfangli micrornainitiateddnazymemotoroperatinginlivingcells AT hongquanzhang micrornainitiateddnazymemotoroperatinginlivingcells AT xchrisle micrornainitiateddnazymemotoroperatinginlivingcells
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A microRNA-initiated DNAzyme motor operating in living cells

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