Unravelling the developmental and functional significance of an ancient Argonaute duplication

The sea anemone Nematostella vectensis expresses miRNAs and two Argonaute (AGO) proteins. Here the authors show that NveAGO1 and NveAGO2 are loaded with overlapping but different sets of miRNAs and that NveAGO2 binds both miRNAs and endo-siRNAs. Both AGO proteins are essential for development.

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Autores principales:	Arie Fridrich, Vengamanaidu Modepalli, Magda Lewandowska, Reuven Aharoni, Yehu Moran
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4adaff49cd994a73b15d96b16db66758
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spelling	oai:doaj.org-article:4adaff49cd994a73b15d96b16db667582021-12-02T14:41:23ZUnravelling the developmental and functional significance of an ancient Argonaute duplication10.1038/s41467-020-20003-82041-1723https://doaj.org/article/4adaff49cd994a73b15d96b16db667582020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20003-8https://doaj.org/toc/2041-1723The sea anemone Nematostella vectensis expresses miRNAs and two Argonaute (AGO) proteins. Here the authors show that NveAGO1 and NveAGO2 are loaded with overlapping but different sets of miRNAs and that NveAGO2 binds both miRNAs and endo-siRNAs. Both AGO proteins are essential for development.Arie FridrichVengamanaidu ModepalliMagda LewandowskaReuven AharoniYehu MoranNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Arie Fridrich Vengamanaidu Modepalli Magda Lewandowska Reuven Aharoni Yehu Moran Unravelling the developmental and functional significance of an ancient Argonaute duplication
description	The sea anemone Nematostella vectensis expresses miRNAs and two Argonaute (AGO) proteins. Here the authors show that NveAGO1 and NveAGO2 are loaded with overlapping but different sets of miRNAs and that NveAGO2 binds both miRNAs and endo-siRNAs. Both AGO proteins are essential for development.
format	article
author	Arie Fridrich Vengamanaidu Modepalli Magda Lewandowska Reuven Aharoni Yehu Moran
author_facet	Arie Fridrich Vengamanaidu Modepalli Magda Lewandowska Reuven Aharoni Yehu Moran
author_sort	Arie Fridrich
title	Unravelling the developmental and functional significance of an ancient Argonaute duplication
title_short	Unravelling the developmental and functional significance of an ancient Argonaute duplication
title_full	Unravelling the developmental and functional significance of an ancient Argonaute duplication
title_fullStr	Unravelling the developmental and functional significance of an ancient Argonaute duplication
title_full_unstemmed	Unravelling the developmental and functional significance of an ancient Argonaute duplication
title_sort	unravelling the developmental and functional significance of an ancient argonaute duplication
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4adaff49cd994a73b15d96b16db66758
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Unravelling the developmental and functional significance of an ancient Argonaute duplication

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