Unravelling the developmental and functional significance of an ancient Argonaute duplication

The sea anemone Nematostella vectensis expresses miRNAs and two Argonaute (AGO) proteins. Here the authors show that NveAGO1 and NveAGO2 are loaded with overlapping but different sets of miRNAs and that NveAGO2 binds both miRNAs and endo-siRNAs. Both AGO proteins are essential for development.

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Auteurs principaux: Arie Fridrich, Vengamanaidu Modepalli, Magda Lewandowska, Reuven Aharoni, Yehu Moran
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/4adaff49cd994a73b15d96b16db66758
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