Co-factor-free aggregation of tau into seeding-competent RNA-sequestering amyloid fibrils

The authors present a method for the conversion of full-length tau protein into seeding-competent amyloid fibrils without heparin or other negatively charged co-factors, which could be useful for studying the effects of post-translational modifications on Tau aggregation as well as to identify poten...

Full description

Saved in:
Bibliographic Details
Main Authors: Pijush Chakraborty, Gwladys Rivière, Shu Liu, Alain Ibáñez de Opakua, Rıza Dervişoğlu, Alina Hebestreit, Loren B. Andreas, Ina M. Vorberg, Markus Zweckstetter
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Q
Online Access:https://doaj.org/article/4ae08ea82f3e4f1da86a83d9dfe205fb
Tags: Add Tag
No Tags, Be the first to tag this record!