An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses

MicroRNAs (miR) are important regulators of gene transcription, with miR-155 and miR-146a both implicated in macrophage activation. Here the authors show that NF-κB signalling, miR-155 and miR-146a form a complex network of cross-regulations to control gene transcription in macrophages for modulatin...

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Autores principales:	Mati Mann, Arnav Mehta, Jimmy L. Zhao, Kevin Lee, Georgi K. Marinov, Yvette Garcia-Flores, Li-Fan Lu, Alexander Y. Rudensky, David Baltimore
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4ae78de76bc742c580b294dc0c5d59fe
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spelling	oai:doaj.org-article:4ae78de76bc742c580b294dc0c5d59fe2021-12-02T15:37:05ZAn NF-κB-microRNA regulatory network tunes macrophage inflammatory responses10.1038/s41467-017-00972-z2041-1723https://doaj.org/article/4ae78de76bc742c580b294dc0c5d59fe2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00972-zhttps://doaj.org/toc/2041-1723MicroRNAs (miR) are important regulators of gene transcription, with miR-155 and miR-146a both implicated in macrophage activation. Here the authors show that NF-κB signalling, miR-155 and miR-146a form a complex network of cross-regulations to control gene transcription in macrophages for modulating inflammatory responses.Mati MannArnav MehtaJimmy L. ZhaoKevin LeeGeorgi K. MarinovYvette Garcia-FloresLi-Fan LuAlexander Y. RudenskyDavid BaltimoreNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mati Mann Arnav Mehta Jimmy L. Zhao Kevin Lee Georgi K. Marinov Yvette Garcia-Flores Li-Fan Lu Alexander Y. Rudensky David Baltimore An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
description	MicroRNAs (miR) are important regulators of gene transcription, with miR-155 and miR-146a both implicated in macrophage activation. Here the authors show that NF-κB signalling, miR-155 and miR-146a form a complex network of cross-regulations to control gene transcription in macrophages for modulating inflammatory responses.
format	article
author	Mati Mann Arnav Mehta Jimmy L. Zhao Kevin Lee Georgi K. Marinov Yvette Garcia-Flores Li-Fan Lu Alexander Y. Rudensky David Baltimore
author_facet	Mati Mann Arnav Mehta Jimmy L. Zhao Kevin Lee Georgi K. Marinov Yvette Garcia-Flores Li-Fan Lu Alexander Y. Rudensky David Baltimore
author_sort	Mati Mann
title	An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
title_short	An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
title_full	An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
title_fullStr	An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
title_full_unstemmed	An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
title_sort	nf-κb-microrna regulatory network tunes macrophage inflammatory responses
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/4ae78de76bc742c580b294dc0c5d59fe
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An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses

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