Kinetic CRAC uncovers a role for Nab3 in determining gene expression profiles during stress

Protein RNA interactions are dynamic and regulated in response to environmental changes. Here the authors describe ‘kinetic CRAC’, an approach that allows time resolved analyses of protein RNA interactions with minute time point resolution and apply it to gain insight into the function of the RNA-bi...

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Autores principales: Rob van Nues, Gabriele Schweikert, Erica de Leau, Alina Selega, Andrew Langford, Ryan Franklin, Ira Iosub, Peter Wadsworth, Guido Sanguinetti, Sander Granneman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/4af8f874266d433eb3ee39b859f6ee20
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spelling oai:doaj.org-article:4af8f874266d433eb3ee39b859f6ee202021-12-02T13:57:55ZKinetic CRAC uncovers a role for Nab3 in determining gene expression profiles during stress10.1038/s41467-017-00025-52041-1723https://doaj.org/article/4af8f874266d433eb3ee39b859f6ee202017-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00025-5https://doaj.org/toc/2041-1723Protein RNA interactions are dynamic and regulated in response to environmental changes. Here the authors describe ‘kinetic CRAC’, an approach that allows time resolved analyses of protein RNA interactions with minute time point resolution and apply it to gain insight into the function of the RNA-binding protein Nab3.Rob van NuesGabriele SchweikertErica de LeauAlina SelegaAndrew LangfordRyan FranklinIra IosubPeter WadsworthGuido SanguinettiSander GrannemanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Rob van Nues
Gabriele Schweikert
Erica de Leau
Alina Selega
Andrew Langford
Ryan Franklin
Ira Iosub
Peter Wadsworth
Guido Sanguinetti
Sander Granneman
Kinetic CRAC uncovers a role for Nab3 in determining gene expression profiles during stress
description Protein RNA interactions are dynamic and regulated in response to environmental changes. Here the authors describe ‘kinetic CRAC’, an approach that allows time resolved analyses of protein RNA interactions with minute time point resolution and apply it to gain insight into the function of the RNA-binding protein Nab3.
format article
author Rob van Nues
Gabriele Schweikert
Erica de Leau
Alina Selega
Andrew Langford
Ryan Franklin
Ira Iosub
Peter Wadsworth
Guido Sanguinetti
Sander Granneman
author_facet Rob van Nues
Gabriele Schweikert
Erica de Leau
Alina Selega
Andrew Langford
Ryan Franklin
Ira Iosub
Peter Wadsworth
Guido Sanguinetti
Sander Granneman
author_sort Rob van Nues
title Kinetic CRAC uncovers a role for Nab3 in determining gene expression profiles during stress
title_short Kinetic CRAC uncovers a role for Nab3 in determining gene expression profiles during stress
title_full Kinetic CRAC uncovers a role for Nab3 in determining gene expression profiles during stress
title_fullStr Kinetic CRAC uncovers a role for Nab3 in determining gene expression profiles during stress
title_full_unstemmed Kinetic CRAC uncovers a role for Nab3 in determining gene expression profiles during stress
title_sort kinetic crac uncovers a role for nab3 in determining gene expression profiles during stress
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/4af8f874266d433eb3ee39b859f6ee20
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