Hyperglycemia and blood pressure treatment goal: a cross sectional survey of 18350 patients with type 2 diabetes in 77 tertiary hospitals in China.

<h4>Objective</h4>To investigate the association of hyperglycemia with blood pressure control goal in the patients with type 2 diabetes (T2D) cared by tertiary hospitals in China.<h4>Study design and methods</h4>A cross sectional survey of 29442 patients was conducted in 77 t...

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Autores principales: Linong Ji, Xinyue Zhi, Juming Lu, Xiaohui Guo, Wenying Yang, Weiping Jia, Dajin Zou, Zhiguang Zhou, Qiuhe Ji, Dalong Zhu, Lixin Shi, Jianping Weng
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Publicado: Public Library of Science (PLoS) 2014
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spelling oai:doaj.org-article:4afec61fa2af416e9d04d7c3aa1d58e72021-11-25T06:04:48ZHyperglycemia and blood pressure treatment goal: a cross sectional survey of 18350 patients with type 2 diabetes in 77 tertiary hospitals in China.1932-620310.1371/journal.pone.0103507https://doaj.org/article/4afec61fa2af416e9d04d7c3aa1d58e72014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25121493/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Objective</h4>To investigate the association of hyperglycemia with blood pressure control goal in the patients with type 2 diabetes (T2D) cared by tertiary hospitals in China.<h4>Study design and methods</h4>A cross sectional survey of 29442 patients was conducted in 77 tertiary hospitals in 4 major cities in China in 2011 and 18350 of them without known hypertension were used in the analysis. Univariable and multivariable logistic regression analysis stratified on cities and hospitals was performed to obtain odds ratio of factors of interest for achievement of the blood pressure treatment goal, i.e., 140/80 mmHg as recommended by American Diabetes Association (ADA). Sensitivity analysis was performed after re-inclusion of 11902 patients with diagnosed hypertension. Findings from were further replicated in patients with T2D recruited using the same protocol from tertiary hospitals located in other central cities in China.<h4>Results</h4>The mean age was 58.2 (SD: 11.3) years and 53.3% were male, with a median of 4 years of disease duration. A total of 12129 patients (58.2%) did not achieve the ADA recommended goal for BP control. After adjusting for covariables, hyperglycemia was associated with failure to achieve the BP goal (OR of HbA1c at 6.5%-6.9% vs. <6.0%: 1.22, 95%CI: 1.08 to 1.39; OR of 7.0%-7.0% vs. <6.0%: 1.37, 1.21 to 1.54 and OR of ≥ 8.0% vs. <6.0%: 1.22, 95%CI: 1.08 to 1.38). The sensitivity analysis and the replication analysis showed similar results.<h4>Conclusions</h4>Hyperglycemia defined as HbA1c ≥ 6.5% increased the risk of failure to achieve the BP goal in T2D patients.Linong JiXinyue ZhiJuming LuXiaohui GuoWenying YangWeiping JiaDajin ZouZhiguang ZhouQiuhe JiDalong ZhuLixin ShiJianping WengPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 8, p e103507 (2014)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Linong Ji
Xinyue Zhi
Juming Lu
Xiaohui Guo
Wenying Yang
Weiping Jia
Dajin Zou
Zhiguang Zhou
Qiuhe Ji
Dalong Zhu
Lixin Shi
Jianping Weng
Hyperglycemia and blood pressure treatment goal: a cross sectional survey of 18350 patients with type 2 diabetes in 77 tertiary hospitals in China.
description <h4>Objective</h4>To investigate the association of hyperglycemia with blood pressure control goal in the patients with type 2 diabetes (T2D) cared by tertiary hospitals in China.<h4>Study design and methods</h4>A cross sectional survey of 29442 patients was conducted in 77 tertiary hospitals in 4 major cities in China in 2011 and 18350 of them without known hypertension were used in the analysis. Univariable and multivariable logistic regression analysis stratified on cities and hospitals was performed to obtain odds ratio of factors of interest for achievement of the blood pressure treatment goal, i.e., 140/80 mmHg as recommended by American Diabetes Association (ADA). Sensitivity analysis was performed after re-inclusion of 11902 patients with diagnosed hypertension. Findings from were further replicated in patients with T2D recruited using the same protocol from tertiary hospitals located in other central cities in China.<h4>Results</h4>The mean age was 58.2 (SD: 11.3) years and 53.3% were male, with a median of 4 years of disease duration. A total of 12129 patients (58.2%) did not achieve the ADA recommended goal for BP control. After adjusting for covariables, hyperglycemia was associated with failure to achieve the BP goal (OR of HbA1c at 6.5%-6.9% vs. <6.0%: 1.22, 95%CI: 1.08 to 1.39; OR of 7.0%-7.0% vs. <6.0%: 1.37, 1.21 to 1.54 and OR of ≥ 8.0% vs. <6.0%: 1.22, 95%CI: 1.08 to 1.38). The sensitivity analysis and the replication analysis showed similar results.<h4>Conclusions</h4>Hyperglycemia defined as HbA1c ≥ 6.5% increased the risk of failure to achieve the BP goal in T2D patients.
format article
author Linong Ji
Xinyue Zhi
Juming Lu
Xiaohui Guo
Wenying Yang
Weiping Jia
Dajin Zou
Zhiguang Zhou
Qiuhe Ji
Dalong Zhu
Lixin Shi
Jianping Weng
author_facet Linong Ji
Xinyue Zhi
Juming Lu
Xiaohui Guo
Wenying Yang
Weiping Jia
Dajin Zou
Zhiguang Zhou
Qiuhe Ji
Dalong Zhu
Lixin Shi
Jianping Weng
author_sort Linong Ji
title Hyperglycemia and blood pressure treatment goal: a cross sectional survey of 18350 patients with type 2 diabetes in 77 tertiary hospitals in China.
title_short Hyperglycemia and blood pressure treatment goal: a cross sectional survey of 18350 patients with type 2 diabetes in 77 tertiary hospitals in China.
title_full Hyperglycemia and blood pressure treatment goal: a cross sectional survey of 18350 patients with type 2 diabetes in 77 tertiary hospitals in China.
title_fullStr Hyperglycemia and blood pressure treatment goal: a cross sectional survey of 18350 patients with type 2 diabetes in 77 tertiary hospitals in China.
title_full_unstemmed Hyperglycemia and blood pressure treatment goal: a cross sectional survey of 18350 patients with type 2 diabetes in 77 tertiary hospitals in China.
title_sort hyperglycemia and blood pressure treatment goal: a cross sectional survey of 18350 patients with type 2 diabetes in 77 tertiary hospitals in china.
publisher Public Library of Science (PLoS)
publishDate 2014
url https://doaj.org/article/4afec61fa2af416e9d04d7c3aa1d58e7
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