Long-lived unipotent Blimp1-positive luminal stem cells drive mammary gland organogenesis throughout adult life

The role of stem/progenitor cell populations in mammary gland morphogenesis is not well understood. Here, the authors show that a transcriptional repressor, Blimp1, is expressed in a rare luminal stem cell population, which contribute to duct formation, and survive multiple rounds of pregnancy and i...

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Autores principales: Salah Elias, Marc A. Morgan, Elizabeth K. Bikoff, Elizabeth J. Robertson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/4aff0135d8cd4c069ea5ad5641f3cb92
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