Orbitofrontal control of visual cortex gain promotes visual associative learning

The orbitofrontal cortex (OFC) encodes expected outcomes and plays a key role in outcome-guided behavior. The authors show here that the top-down projection from the OFC to the visual cortex drives visual associative learning by modulating the response gain of V1 neurons to non-relevant stimuli.

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Detalles Bibliográficos
Autores principales: Dechen Liu, Juan Deng, Zhewei Zhang, Zhi-Yu Zhang, Yan-Gang Sun, Tianming Yang, Haishan Yao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/4afff2f4f93b4237bb1ae9e710e43a2f
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Descripción
Sumario:The orbitofrontal cortex (OFC) encodes expected outcomes and plays a key role in outcome-guided behavior. The authors show here that the top-down projection from the OFC to the visual cortex drives visual associative learning by modulating the response gain of V1 neurons to non-relevant stimuli.