Orbitofrontal control of visual cortex gain promotes visual associative learning

The orbitofrontal cortex (OFC) encodes expected outcomes and plays a key role in outcome-guided behavior. The authors show here that the top-down projection from the OFC to the visual cortex drives visual associative learning by modulating the response gain of V1 neurons to non-relevant stimuli.

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Autores principales: Dechen Liu, Juan Deng, Zhewei Zhang, Zhi-Yu Zhang, Yan-Gang Sun, Tianming Yang, Haishan Yao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/4afff2f4f93b4237bb1ae9e710e43a2f
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spelling oai:doaj.org-article:4afff2f4f93b4237bb1ae9e710e43a2f2021-12-02T17:51:04ZOrbitofrontal control of visual cortex gain promotes visual associative learning10.1038/s41467-020-16609-72041-1723https://doaj.org/article/4afff2f4f93b4237bb1ae9e710e43a2f2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16609-7https://doaj.org/toc/2041-1723The orbitofrontal cortex (OFC) encodes expected outcomes and plays a key role in outcome-guided behavior. The authors show here that the top-down projection from the OFC to the visual cortex drives visual associative learning by modulating the response gain of V1 neurons to non-relevant stimuli.Dechen LiuJuan DengZhewei ZhangZhi-Yu ZhangYan-Gang SunTianming YangHaishan YaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dechen Liu
Juan Deng
Zhewei Zhang
Zhi-Yu Zhang
Yan-Gang Sun
Tianming Yang
Haishan Yao
Orbitofrontal control of visual cortex gain promotes visual associative learning
description The orbitofrontal cortex (OFC) encodes expected outcomes and plays a key role in outcome-guided behavior. The authors show here that the top-down projection from the OFC to the visual cortex drives visual associative learning by modulating the response gain of V1 neurons to non-relevant stimuli.
format article
author Dechen Liu
Juan Deng
Zhewei Zhang
Zhi-Yu Zhang
Yan-Gang Sun
Tianming Yang
Haishan Yao
author_facet Dechen Liu
Juan Deng
Zhewei Zhang
Zhi-Yu Zhang
Yan-Gang Sun
Tianming Yang
Haishan Yao
author_sort Dechen Liu
title Orbitofrontal control of visual cortex gain promotes visual associative learning
title_short Orbitofrontal control of visual cortex gain promotes visual associative learning
title_full Orbitofrontal control of visual cortex gain promotes visual associative learning
title_fullStr Orbitofrontal control of visual cortex gain promotes visual associative learning
title_full_unstemmed Orbitofrontal control of visual cortex gain promotes visual associative learning
title_sort orbitofrontal control of visual cortex gain promotes visual associative learning
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/4afff2f4f93b4237bb1ae9e710e43a2f
work_keys_str_mv AT dechenliu orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning
AT juandeng orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning
AT zheweizhang orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning
AT zhiyuzhang orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning
AT yangangsun orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning
AT tianmingyang orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning
AT haishanyao orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning
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