Orbitofrontal control of visual cortex gain promotes visual associative learning
The orbitofrontal cortex (OFC) encodes expected outcomes and plays a key role in outcome-guided behavior. The authors show here that the top-down projection from the OFC to the visual cortex drives visual associative learning by modulating the response gain of V1 neurons to non-relevant stimuli.
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Nature Portfolio
2020
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oai:doaj.org-article:4afff2f4f93b4237bb1ae9e710e43a2f2021-12-02T17:51:04ZOrbitofrontal control of visual cortex gain promotes visual associative learning10.1038/s41467-020-16609-72041-1723https://doaj.org/article/4afff2f4f93b4237bb1ae9e710e43a2f2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16609-7https://doaj.org/toc/2041-1723The orbitofrontal cortex (OFC) encodes expected outcomes and plays a key role in outcome-guided behavior. The authors show here that the top-down projection from the OFC to the visual cortex drives visual associative learning by modulating the response gain of V1 neurons to non-relevant stimuli.Dechen LiuJuan DengZhewei ZhangZhi-Yu ZhangYan-Gang SunTianming YangHaishan YaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
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Science Q Dechen Liu Juan Deng Zhewei Zhang Zhi-Yu Zhang Yan-Gang Sun Tianming Yang Haishan Yao Orbitofrontal control of visual cortex gain promotes visual associative learning |
description |
The orbitofrontal cortex (OFC) encodes expected outcomes and plays a key role in outcome-guided behavior. The authors show here that the top-down projection from the OFC to the visual cortex drives visual associative learning by modulating the response gain of V1 neurons to non-relevant stimuli. |
format |
article |
author |
Dechen Liu Juan Deng Zhewei Zhang Zhi-Yu Zhang Yan-Gang Sun Tianming Yang Haishan Yao |
author_facet |
Dechen Liu Juan Deng Zhewei Zhang Zhi-Yu Zhang Yan-Gang Sun Tianming Yang Haishan Yao |
author_sort |
Dechen Liu |
title |
Orbitofrontal control of visual cortex gain promotes visual associative learning |
title_short |
Orbitofrontal control of visual cortex gain promotes visual associative learning |
title_full |
Orbitofrontal control of visual cortex gain promotes visual associative learning |
title_fullStr |
Orbitofrontal control of visual cortex gain promotes visual associative learning |
title_full_unstemmed |
Orbitofrontal control of visual cortex gain promotes visual associative learning |
title_sort |
orbitofrontal control of visual cortex gain promotes visual associative learning |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/4afff2f4f93b4237bb1ae9e710e43a2f |
work_keys_str_mv |
AT dechenliu orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning AT juandeng orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning AT zheweizhang orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning AT zhiyuzhang orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning AT yangangsun orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning AT tianmingyang orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning AT haishanyao orbitofrontalcontrolofvisualcortexgainpromotesvisualassociativelearning |
_version_ |
1718379283863306240 |