Hemodialysis exacerbates proteolytic imbalance and pro-fibrotic platelet dysfunction

Hemodialysis exacerbates proteolytic imbalance and pro-fibrotic platelet dysfunction

Abstract Multi-organ fibrosis among end stage renal disease (ESRD) patients cannot be explained by uremia alone. Despite mitigation of thrombosis during hemodialysis (HD), subsequent platelet dysfunction and tissue dysregulation are less understood. We comprehensively profiled plasma and platelets f...

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Autores principales: Aaron J. Velasquez-Mao, Mark A. Velasquez, Zhengxiong Hui, Denise Armas-Ayon, Jingshen Wang, Moriel H. Vandsburger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/4b0723b32a1342b4a390eadbc03000a0
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