360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2-year outcomes
Tomoki Sato,1 Takahiro Kawaji,1 Akira Hirata,2 Takanori Mizoguchi3 1Sato Eye and Internal Medicine Clinic, Arao City, Kumamoto, Japan; 2Hayashi Eye Hospital, Hakata-ku, Fukuoka, Japan; 3Mizoguchi Eye Clinic, Sasebo, Nagasaki, Japan Purpose: The purpose of this study was to evaluate the efficacy of...
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Dove Medical Press
2018
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oai:doaj.org-article:4b1645be040449618af572d542bf20c22021-12-02T04:44:58Z360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2-year outcomes1177-5483https://doaj.org/article/4b1645be040449618af572d542bf20c22018-05-01T00:00:00Zhttps://www.dovepress.com/360-degree-suture-trabeculotomy-ab-interno-to-treat-open-angle-glaucom-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Tomoki Sato,1 Takahiro Kawaji,1 Akira Hirata,2 Takanori Mizoguchi3 1Sato Eye and Internal Medicine Clinic, Arao City, Kumamoto, Japan; 2Hayashi Eye Hospital, Hakata-ku, Fukuoka, Japan; 3Mizoguchi Eye Clinic, Sasebo, Nagasaki, Japan Purpose: The purpose of this study was to evaluate the efficacy of 360-degree suture trabeculotomy (360S-LOT) ab interno for treating open-angle glaucoma (OAG). Risk factors of surgical failure were examined. Patients and methods: 360S-LOT ab interno alone was performed for patients with uncontrolled OAG, and combined 360S-LOT ab interno/phacoemulsification was performed for patients with controlled OAG with a visually significant cataract between March 2014 and September 2015 at a single center. The patients were prospectively followed for 2 years. The main outcome measures included 2-year intraocular pressure (IOP), number of anti-glaucoma medications used, postoperative complications, and predictive factors of surgical failure. Kaplan–Meier analysis was performed, with surgical success (with or without medication use) defined as postoperative IOP ≤15 mmHg and IOP reduction ≥20% (criterion A) or IOP ≤12 mmHg and IOP reduction ≥30% (criterion B). Predictive factors were evaluated using Cox proportional hazard ratios. Results: A total of 64 eyes of 64 patients were included, and 50 (78%) eyes of 64 eyes underwent a phacoemulsification combination procedure. Surgery significantly reduced IOP from 18.4 ± 2.9 mmHg before surgery to 13.4 ± 3.0 mmHg after surgery (P < 0.001). Patients used an average of 1.8 ± 1.5 medications before surgery and 1.3 ± 1.5 medications after surgery (P = 0.101). No serious postoperative complications were observed. The probability of surgical success was 49.2% and 16.0% using criteria A and B, respectively. No risk factors of surgical failure were identified. Conclusion: The 360S-LOT ab interno procedure is a favorable option for treating eyes with mild or moderate OAG. Keywords: 360-degree suture trabeculotomy ab interno, open-angle glaucoma, minimally invasive glaucoma surgery, phacoemulsificationSato TKawaji THirata AMizoguchi TDove Medical Pressarticle360-degree suture trabeculotomy ab internoopen-angle glaucomaminimally invasive glaucoma surgeryphacoemulsificationOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 915-923 (2018) |
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360-degree suture trabeculotomy ab interno open-angle glaucoma minimally invasive glaucoma surgery phacoemulsification Ophthalmology RE1-994 |
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360-degree suture trabeculotomy ab interno open-angle glaucoma minimally invasive glaucoma surgery phacoemulsification Ophthalmology RE1-994 Sato T Kawaji T Hirata A Mizoguchi T 360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2-year outcomes |
| description |
Tomoki Sato,1 Takahiro Kawaji,1 Akira Hirata,2 Takanori Mizoguchi3 1Sato Eye and Internal Medicine Clinic, Arao City, Kumamoto, Japan; 2Hayashi Eye Hospital, Hakata-ku, Fukuoka, Japan; 3Mizoguchi Eye Clinic, Sasebo, Nagasaki, Japan Purpose: The purpose of this study was to evaluate the efficacy of 360-degree suture trabeculotomy (360S-LOT) ab interno for treating open-angle glaucoma (OAG). Risk factors of surgical failure were examined. Patients and methods: 360S-LOT ab interno alone was performed for patients with uncontrolled OAG, and combined 360S-LOT ab interno/phacoemulsification was performed for patients with controlled OAG with a visually significant cataract between March 2014 and September 2015 at a single center. The patients were prospectively followed for 2 years. The main outcome measures included 2-year intraocular pressure (IOP), number of anti-glaucoma medications used, postoperative complications, and predictive factors of surgical failure. Kaplan–Meier analysis was performed, with surgical success (with or without medication use) defined as postoperative IOP ≤15 mmHg and IOP reduction ≥20% (criterion A) or IOP ≤12 mmHg and IOP reduction ≥30% (criterion B). Predictive factors were evaluated using Cox proportional hazard ratios. Results: A total of 64 eyes of 64 patients were included, and 50 (78%) eyes of 64 eyes underwent a phacoemulsification combination procedure. Surgery significantly reduced IOP from 18.4 ± 2.9 mmHg before surgery to 13.4 ± 3.0 mmHg after surgery (P < 0.001). Patients used an average of 1.8 ± 1.5 medications before surgery and 1.3 ± 1.5 medications after surgery (P = 0.101). No serious postoperative complications were observed. The probability of surgical success was 49.2% and 16.0% using criteria A and B, respectively. No risk factors of surgical failure were identified. Conclusion: The 360S-LOT ab interno procedure is a favorable option for treating eyes with mild or moderate OAG. Keywords: 360-degree suture trabeculotomy ab interno, open-angle glaucoma, minimally invasive glaucoma surgery, phacoemulsification |
| format |
article |
| author |
Sato T Kawaji T Hirata A Mizoguchi T |
| author_facet |
Sato T Kawaji T Hirata A Mizoguchi T |
| author_sort |
Sato T |
| title |
360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2-year outcomes |
| title_short |
360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2-year outcomes |
| title_full |
360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2-year outcomes |
| title_fullStr |
360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2-year outcomes |
| title_full_unstemmed |
360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2-year outcomes |
| title_sort |
360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2-year outcomes |
| publisher |
Dove Medical Press |
| publishDate |
2018 |
| url |
https://doaj.org/article/4b1645be040449618af572d542bf20c2 |
| work_keys_str_mv |
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| _version_ |
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