The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site

CcrM is a cell cycle-regulated DNA methyltransferase that methylates an adenine within a specific sequence following replication in the gram negative bacterium Caulobacter crescentus. Here the authors present a crystal structure of DNA-bound CcrM that reveals the molecular mechanism leading to seque...

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Autores principales:	John R. Horton, Clayton B. Woodcock, Sifa B. Opot, Norbert O. Reich, Xing Zhang, Xiaodong Cheng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4b19d54306f64a6a987f9f163c1d7c87
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spelling	oai:doaj.org-article:4b19d54306f64a6a987f9f163c1d7c872021-12-02T15:35:50ZThe cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site10.1038/s41467-019-12498-72041-1723https://doaj.org/article/4b19d54306f64a6a987f9f163c1d7c872019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12498-7https://doaj.org/toc/2041-1723CcrM is a cell cycle-regulated DNA methyltransferase that methylates an adenine within a specific sequence following replication in the gram negative bacterium Caulobacter crescentus. Here the authors present a crystal structure of DNA-bound CcrM that reveals the molecular mechanism leading to sequence-specific methylation.John R. HortonClayton B. WoodcockSifa B. OpotNorbert O. ReichXing ZhangXiaodong ChengNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q John R. Horton Clayton B. Woodcock Sifa B. Opot Norbert O. Reich Xing Zhang Xiaodong Cheng The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site
description	CcrM is a cell cycle-regulated DNA methyltransferase that methylates an adenine within a specific sequence following replication in the gram negative bacterium Caulobacter crescentus. Here the authors present a crystal structure of DNA-bound CcrM that reveals the molecular mechanism leading to sequence-specific methylation.
format	article
author	John R. Horton Clayton B. Woodcock Sifa B. Opot Norbert O. Reich Xing Zhang Xiaodong Cheng
author_facet	John R. Horton Clayton B. Woodcock Sifa B. Opot Norbert O. Reich Xing Zhang Xiaodong Cheng
author_sort	John R. Horton
title	The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site
title_short	The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site
title_full	The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site
title_fullStr	The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site
title_full_unstemmed	The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site
title_sort	cell cycle-regulated dna adenine methyltransferase ccrm opens a bubble at its dna recognition site
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/4b19d54306f64a6a987f9f163c1d7c87
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The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site

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