Sensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in CO intoxication

Mao et al. report highly sensitive quantification of carbon monoxide with a simple colorimetric assay, exploiting a synthetic supramolecular compound, hemoCD1. It can reveal distribution of CO in organs including the brain and can also serve as a CO scavenger for residual CO accumulated in organs. F...

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Autores principales:	Qiyue Mao, Akira T. Kawaguchi, Shun Mizobata, Roberto Motterlini, Roberta Foresti, Hiroaki Kitagishi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/4b1f78dee8e74f8090c69506a80dd15a
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spelling	oai:doaj.org-article:4b1f78dee8e74f8090c69506a80dd15a2021-12-02T13:27:03ZSensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in CO intoxication10.1038/s42003-021-01880-12399-3642https://doaj.org/article/4b1f78dee8e74f8090c69506a80dd15a2021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01880-1https://doaj.org/toc/2399-3642Mao et al. report highly sensitive quantification of carbon monoxide with a simple colorimetric assay, exploiting a synthetic supramolecular compound, hemoCD1. It can reveal distribution of CO in organs including the brain and can also serve as a CO scavenger for residual CO accumulated in organs. Finally, the authors showed circulating hemoglobin plays a protective role in CO intoxication.Qiyue MaoAkira T. KawaguchiShun MizobataRoberto MotterliniRoberta ForestiHiroaki KitagishiNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Qiyue Mao Akira T. Kawaguchi Shun Mizobata Roberto Motterlini Roberta Foresti Hiroaki Kitagishi Sensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in CO intoxication
description	Mao et al. report highly sensitive quantification of carbon monoxide with a simple colorimetric assay, exploiting a synthetic supramolecular compound, hemoCD1. It can reveal distribution of CO in organs including the brain and can also serve as a CO scavenger for residual CO accumulated in organs. Finally, the authors showed circulating hemoglobin plays a protective role in CO intoxication.
format	article
author	Qiyue Mao Akira T. Kawaguchi Shun Mizobata Roberto Motterlini Roberta Foresti Hiroaki Kitagishi
author_facet	Qiyue Mao Akira T. Kawaguchi Shun Mizobata Roberto Motterlini Roberta Foresti Hiroaki Kitagishi
author_sort	Qiyue Mao
title	Sensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in CO intoxication
title_short	Sensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in CO intoxication
title_full	Sensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in CO intoxication
title_fullStr	Sensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in CO intoxication
title_full_unstemmed	Sensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in CO intoxication
title_sort	sensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in co intoxication
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4b1f78dee8e74f8090c69506a80dd15a
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Sensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in CO intoxication

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