A cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution

<p>In dissolution-dynamic nuclear polarization, a hyperpolarized solid is dissolved with a jet of hot solvent. The solution is then transferred to a secondary magnet, where spectra can be recorded with improved sensitivity. In bullet-dynamic nuclear polarization this order is reversed. Pressu...

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Autores principales:	K. Kouřil, M. Gramberg, M. Jurkutat, H. Kouřilová, B. Meier
Formato:	article
Lenguaje:	EN
Publicado:	Copernicus Publications 2021
Materias:	Electricity and magnetism QC501-766
Acceso en línea:	https://doaj.org/article/4b20308a757a4c108e81c246fa9d9576
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id	oai:doaj.org-article:4b20308a757a4c108e81c246fa9d9576
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spelling	oai:doaj.org-article:4b20308a757a4c108e81c246fa9d95762021-11-11T07:28:44ZA cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution10.5194/mr-2-815-20212699-0016https://doaj.org/article/4b20308a757a4c108e81c246fa9d95762021-11-01T00:00:00Zhttps://mr.copernicus.org/articles/2/815/2021/mr-2-815-2021.pdfhttps://doaj.org/toc/2699-0016<p>In dissolution-dynamic nuclear polarization, a hyperpolarized solid is dissolved with a jet of hot solvent. The solution is then transferred to a secondary magnet, where spectra can be recorded with improved sensitivity. In bullet-dynamic nuclear polarization this order is reversed. Pressurized gas is used to rapidly transfer the hyperpolarized solid to the secondary magnet, and the hyperpolarized solid is dissolved only upon arrival. A potential advantage of this approach is that it may avoid excessive dilution and the associated signal loss, in particular for small sample quantities. Previously, we have shown that liquid-state NMR spectra with polarization levels of up to 30 % may be recorded within less than 1 s after the departure of the hyperpolarized solid from the polarizing magnet. The resolution of the recorded spectra however was limited. The system consumed significant amounts of liquid helium, and substantial manual work was required in between experiments to prepare for the next shot. Here, we present a new bullet-DNP (dynamic nuclear polarization) system that addresses these limitations.</p>K. KouřilM. GrambergM. JurkutatH. KouřilováB. MeierB. MeierCopernicus PublicationsarticleElectricity and magnetismQC501-766ENMagnetic Resonance, Vol 2, Pp 815-825 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Electricity and magnetism QC501-766
spellingShingle	Electricity and magnetism QC501-766 K. Kouřil M. Gramberg M. Jurkutat H. Kouřilová B. Meier B. Meier A cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution
description	<p>In dissolution-dynamic nuclear polarization, a hyperpolarized solid is dissolved with a jet of hot solvent. The solution is then transferred to a secondary magnet, where spectra can be recorded with improved sensitivity. In bullet-dynamic nuclear polarization this order is reversed. Pressurized gas is used to rapidly transfer the hyperpolarized solid to the secondary magnet, and the hyperpolarized solid is dissolved only upon arrival. A potential advantage of this approach is that it may avoid excessive dilution and the associated signal loss, in particular for small sample quantities. Previously, we have shown that liquid-state NMR spectra with polarization levels of up to 30 % may be recorded within less than 1 s after the departure of the hyperpolarized solid from the polarizing magnet. The resolution of the recorded spectra however was limited. The system consumed significant amounts of liquid helium, and substantial manual work was required in between experiments to prepare for the next shot. Here, we present a new bullet-DNP (dynamic nuclear polarization) system that addresses these limitations.</p>
format	article
author	K. Kouřil M. Gramberg M. Jurkutat H. Kouřilová B. Meier B. Meier
author_facet	K. Kouřil M. Gramberg M. Jurkutat H. Kouřilová B. Meier B. Meier
author_sort	K. Kouřil
title	A cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution
title_short	A cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution
title_full	A cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution
title_fullStr	A cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution
title_full_unstemmed	A cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution
title_sort	cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution
publisher	Copernicus Publications
publishDate	2021
url	https://doaj.org/article/4b20308a757a4c108e81c246fa9d9576
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A cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution

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