Portal hypertension: an uncommon clinical manifestation of Takayasu arteritis in a 9-year-old child

Cristina N Herrera, Javier E Tomala-Haz Department of Pediatric Rheumatology, Dr Roberto Gilbert Children’s Hospital, Guayaquil, Ecuador Abstract: Takayasu arteritis (TA) is the third most common childhood vasculitis and its clinical manifestations depend on the arteries...

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Autores principales:	Herrera CN, Tomala-Haz JE
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	Takayasu Arteritis Coronary Aneurysm Children Portal Hypertension. Diseases of the musculoskeletal system RC925-935
Acceso en línea:	https://doaj.org/article/4b22a492252e46fbba1487967473c640
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spelling	oai:doaj.org-article:4b22a492252e46fbba1487967473c6402021-12-02T02:42:54ZPortal hypertension: an uncommon clinical manifestation of Takayasu arteritis in a 9-year-old child1179-156Xhttps://doaj.org/article/4b22a492252e46fbba1487967473c6402016-11-01T00:00:00Zhttps://www.dovepress.com/portal-hypertension-an-uncommon-clinical-manifestation-of-takayasu-art-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XCristina N Herrera, Javier E Tomala-Haz Department of Pediatric Rheumatology, Dr Roberto Gilbert Children’s Hospital, Guayaquil, Ecuador Abstract: Takayasu arteritis (TA) is the third most common childhood vasculitis and its clinical manifestations depend on the arteries involved. We report a case of a 9-year-old boy with multiple aneurysms in carotid and iliac arteries, subclavian and coronary arteries, and abdominal aorta. At the age of 7 years, he presented with recurrent fever and hepatosplenomegaly. An angio-computed tomography scan showed aneurysms in the left subclavian artery, abdominal aorta, and both proximal iliac arteries. He was diagnosed with TA and was treated with corticosteroids, aspirin, and enalapril. One year later, he was admitted to Dr Roberto Gilbert Children’s Hospital because of intracranial hemorrhage. Angiography revealed enlargement of aneurysms enlargement and new aneurysms. He also developed portal hypertension. Treatment with intravenous corticosteroids, azathioprine, and monthly intravenous cyclophosphamide was begun. After 6 months of no improvement, infliximab was begun. The aim of this article was to report the concurrence of coronary involvement and portal vein hypertension in pediatric TA because there were scarce reports on this matter. Keywords: Takayasu arteritis, coronary aneurysm, children, portal hypertensionHerrera CNTomala-Haz JEDove Medical PressarticleTakayasu ArteritisCoronary AneurysmChildrenPortal Hypertension.Diseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 8, Pp 115-118 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Takayasu Arteritis Coronary Aneurysm Children Portal Hypertension. Diseases of the musculoskeletal system RC925-935
spellingShingle	Takayasu Arteritis Coronary Aneurysm Children Portal Hypertension. Diseases of the musculoskeletal system RC925-935 Herrera CN Tomala-Haz JE Portal hypertension: an uncommon clinical manifestation of Takayasu arteritis in a 9-year-old child
description	Cristina N Herrera, Javier E Tomala-Haz Department of Pediatric Rheumatology, Dr Roberto Gilbert Children’s Hospital, Guayaquil, Ecuador Abstract: Takayasu arteritis (TA) is the third most common childhood vasculitis and its clinical manifestations depend on the arteries involved. We report a case of a 9-year-old boy with multiple aneurysms in carotid and iliac arteries, subclavian and coronary arteries, and abdominal aorta. At the age of 7 years, he presented with recurrent fever and hepatosplenomegaly. An angio-computed tomography scan showed aneurysms in the left subclavian artery, abdominal aorta, and both proximal iliac arteries. He was diagnosed with TA and was treated with corticosteroids, aspirin, and enalapril. One year later, he was admitted to Dr Roberto Gilbert Children’s Hospital because of intracranial hemorrhage. Angiography revealed enlargement of aneurysms enlargement and new aneurysms. He also developed portal hypertension. Treatment with intravenous corticosteroids, azathioprine, and monthly intravenous cyclophosphamide was begun. After 6 months of no improvement, infliximab was begun. The aim of this article was to report the concurrence of coronary involvement and portal vein hypertension in pediatric TA because there were scarce reports on this matter. Keywords: Takayasu arteritis, coronary aneurysm, children, portal hypertension
format	article
author	Herrera CN Tomala-Haz JE
author_facet	Herrera CN Tomala-Haz JE
author_sort	Herrera CN
title	Portal hypertension: an uncommon clinical manifestation of Takayasu arteritis in a 9-year-old child
title_short	Portal hypertension: an uncommon clinical manifestation of Takayasu arteritis in a 9-year-old child
title_full	Portal hypertension: an uncommon clinical manifestation of Takayasu arteritis in a 9-year-old child
title_fullStr	Portal hypertension: an uncommon clinical manifestation of Takayasu arteritis in a 9-year-old child
title_full_unstemmed	Portal hypertension: an uncommon clinical manifestation of Takayasu arteritis in a 9-year-old child
title_sort	portal hypertension: an uncommon clinical manifestation of takayasu arteritis in a 9-year-old child
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/4b22a492252e46fbba1487967473c640
work_keys_str_mv	AT herreracn portalhypertensionanuncommonclinicalmanifestationoftakayasuarteritisina9yearoldchild AT tomalahazje portalhypertensionanuncommonclinicalmanifestationoftakayasuarteritisina9yearoldchild
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Portal hypertension: an uncommon clinical manifestation of Takayasu arteritis in a 9-year-old child

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