The P. falciparum CSP repeat region contains three distinct epitopes required for protection by antibodies in vivo.

Rare and potent monoclonal antibodies (mAbs) against the Plasmodium falciparum (Pf) circumsporozoite protein (CSP) on infective sporozoites (SPZ) preferentially bind the PfCSP junctional tetrapeptide NPDP or NVDP minor repeats while cross-reacting with NANP central repeats in vitro. The extent to wh...

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Autores principales:	Yevel Flores-Garcia, Lawrence T Wang, Minah Park, Beejan Asady, Azza H Idris, Neville K Kisalu, Christian Muñoz, Lais S Pereira, Joseph R Francica, Robert A Seder, Fidel Zavala
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/4b2f0abc1d8945d0affa55beb09edf04
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

The P. falciparum CSP repeat region contains three distinct epitopes required for protection by antibodies in vivo

por Yevel Flores-Garcia, Lawrence T. Wang, Minah Park, Beejan Asady, Azza H. Idris, Neville K. Kisalu, Christian Muñoz, Lais S. Pereira, Joseph R. Francica, Robert A. Seder, Fidel Zavala
Publicado 2021

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The P. falciparum CSP repeat region contains three distinct epitopes required for protection by antibodies in vivo.

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