Phenotypic memory in Bacillus subtilis links dormancy entry and exit by a spore quantity-quality tradeoff

Bacillus subtilis withstands starvation by forming dormant spores that revive when nutrients become available. Here, Mutlu et al. show that sporulation timing controls spore revival through a phenotypic ‘memory’ that arises from the carry-over of a metabolic enzyme from the vegetative cell into the...

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Autores principales: Alper Mutlu, Stephanie Trauth, Marika Ziesack, Katja Nagler, Jan-Philip Bergeest, Karl Rohr, Nils Becker, Thomas Höfer, Ilka B. Bischofs
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/4b307497ba09401a9b78da3b5ab995c6
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Sumario:Bacillus subtilis withstands starvation by forming dormant spores that revive when nutrients become available. Here, Mutlu et al. show that sporulation timing controls spore revival through a phenotypic ‘memory’ that arises from the carry-over of a metabolic enzyme from the vegetative cell into the spore.