Single-cell transcriptomic analyses of T cells in chronic HCV-infected patients dominated by DAA-induced interferon signaling changes.

Chronic infection with HCV is manifested by dysregulation of innate immune responses and impaired T cell function at multiple levels. These changes may impact susceptibility to other infections, responsiveness to antiviral therapies, vaccine responsiveness, and development of complications such as h...

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Autores principales: Matthew A Burchill, Matthew P Salomon, Lucy Golden-Mason, Amanda Wieland, Ana C Maretti-Mira, Michael Gale, Hugo R Rosen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/4b3c7cb12eb447ffbe8a00b8895b480b
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