High degree of prostate related LUTS in a prospective cross-sectional community study in Ghana (Mamprobi)

Background: Changing voiding patterns, volume and frequency, may sometimes be mistaken for anxiety, stress or increase in fluid consumption. In the aging male population, the commencement of lower urinary tract symptoms (LUTS) may be silent and perceived as “normal” and unrelated to Benign prostatic...

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Autores principales:	George A. Asare, Derick S. Sule, Jared N. Oblitey, Reese Ntiforo, Bernice Asiedu, Brodrick Y. Amoah, Emmanuel L. Lamptey, Daniel K. Afriyie, Benard Ohene Botwe
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Lower urinary tract symptoms (LUTS) Benign prostatic hyperplasia (BPH) Prostate volume Metabolic syndrome (MetS) Science (General) Q1-390 Social sciences (General) H1-99
Acceso en línea:	https://doaj.org/article/4b4165c8250043f4846c1c7e7680d957
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spelling	oai:doaj.org-article:4b4165c8250043f4846c1c7e7680d9572021-12-02T05:02:59ZHigh degree of prostate related LUTS in a prospective cross-sectional community study in Ghana (Mamprobi)2405-844010.1016/j.heliyon.2021.e08391https://doaj.org/article/4b4165c8250043f4846c1c7e7680d9572021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2405844021024944https://doaj.org/toc/2405-8440Background: Changing voiding patterns, volume and frequency, may sometimes be mistaken for anxiety, stress or increase in fluid consumption. In the aging male population, the commencement of lower urinary tract symptoms (LUTS) may be silent and perceived as “normal” and unrelated to Benign prostatic enlargement (BPE). The purpose of the study was to determine the prevalence of apparently “silent LUTS” (perceived asymptomatic LUTS) in men in a Ghanaian Community as well as its underlying risk factors. Methods: One hundred and eleven (111) men (40–70 years) were recruited from a community in Ghana. The International Prostate Symptoms Score (IPSS) questionnaire (administered in the local language and English) and ultrasonographic imaging of the prostate volume (PV) were utlized to collect data. IPSS score >7 plus PV > 30 cm3 was definitive of lower urinary tract symptoms. Eighty-one (81) participants were classified “LUTS Negative” (LN) and 30, “LUTS Positive” (LP). Risk factors i.e., cholesterol (CHOL), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), very low-density lipoprotein (VLDL), coronary risk (CR), BMI and Blood Pressure were also determined. Results: The prevalence of LUTS using only IPSS definition alone was 42.3%. However, IPSS in combination with Prostate Volume gave a prevalence of 27.0%. LN subjects had enlarged prostate (41.98%) and LP, 100%. Quality of life (QoL) was better in the LUTS Negative than LUTS Positive group (p < 0.001). In the univariant analysis coronary risk, triglyceride and VLDL contributed to LUTS (p = 0.023, 0.22, 0.22, respectively). In a multivariant analysis HDL-C (p = 0.027), BMI (p = 0.047) and triglyceride (p = 0.019) significantly contributed to LUTS. Conclusions: The prevalence of LUTS (42.3%) is high. Components of Metabolic Syndrome- HDL-C, BMI, and coronary risk were associated with LUTS. This emphasizes the need for community education.George A. AsareDerick S. SuleJared N. ObliteyReese NtiforoBernice AsieduBrodrick Y. AmoahEmmanuel L. LampteyDaniel K. AfriyieBenard Ohene BotweElsevierarticleLower urinary tract symptoms (LUTS)Benign prostatic hyperplasia (BPH)Prostate volumeMetabolic syndrome (MetS)Science (General)Q1-390Social sciences (General)H1-99ENHeliyon, Vol 7, Iss 11, Pp e08391- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Lower urinary tract symptoms (LUTS) Benign prostatic hyperplasia (BPH) Prostate volume Metabolic syndrome (MetS) Science (General) Q1-390 Social sciences (General) H1-99
spellingShingle	Lower urinary tract symptoms (LUTS) Benign prostatic hyperplasia (BPH) Prostate volume Metabolic syndrome (MetS) Science (General) Q1-390 Social sciences (General) H1-99 George A. Asare Derick S. Sule Jared N. Oblitey Reese Ntiforo Bernice Asiedu Brodrick Y. Amoah Emmanuel L. Lamptey Daniel K. Afriyie Benard Ohene Botwe High degree of prostate related LUTS in a prospective cross-sectional community study in Ghana (Mamprobi)
description	Background: Changing voiding patterns, volume and frequency, may sometimes be mistaken for anxiety, stress or increase in fluid consumption. In the aging male population, the commencement of lower urinary tract symptoms (LUTS) may be silent and perceived as “normal” and unrelated to Benign prostatic enlargement (BPE). The purpose of the study was to determine the prevalence of apparently “silent LUTS” (perceived asymptomatic LUTS) in men in a Ghanaian Community as well as its underlying risk factors. Methods: One hundred and eleven (111) men (40–70 years) were recruited from a community in Ghana. The International Prostate Symptoms Score (IPSS) questionnaire (administered in the local language and English) and ultrasonographic imaging of the prostate volume (PV) were utlized to collect data. IPSS score >7 plus PV > 30 cm3 was definitive of lower urinary tract symptoms. Eighty-one (81) participants were classified “LUTS Negative” (LN) and 30, “LUTS Positive” (LP). Risk factors i.e., cholesterol (CHOL), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), very low-density lipoprotein (VLDL), coronary risk (CR), BMI and Blood Pressure were also determined. Results: The prevalence of LUTS using only IPSS definition alone was 42.3%. However, IPSS in combination with Prostate Volume gave a prevalence of 27.0%. LN subjects had enlarged prostate (41.98%) and LP, 100%. Quality of life (QoL) was better in the LUTS Negative than LUTS Positive group (p < 0.001). In the univariant analysis coronary risk, triglyceride and VLDL contributed to LUTS (p = 0.023, 0.22, 0.22, respectively). In a multivariant analysis HDL-C (p = 0.027), BMI (p = 0.047) and triglyceride (p = 0.019) significantly contributed to LUTS. Conclusions: The prevalence of LUTS (42.3%) is high. Components of Metabolic Syndrome- HDL-C, BMI, and coronary risk were associated with LUTS. This emphasizes the need for community education.
format	article
author	George A. Asare Derick S. Sule Jared N. Oblitey Reese Ntiforo Bernice Asiedu Brodrick Y. Amoah Emmanuel L. Lamptey Daniel K. Afriyie Benard Ohene Botwe
author_facet	George A. Asare Derick S. Sule Jared N. Oblitey Reese Ntiforo Bernice Asiedu Brodrick Y. Amoah Emmanuel L. Lamptey Daniel K. Afriyie Benard Ohene Botwe
author_sort	George A. Asare
title	High degree of prostate related LUTS in a prospective cross-sectional community study in Ghana (Mamprobi)
title_short	High degree of prostate related LUTS in a prospective cross-sectional community study in Ghana (Mamprobi)
title_full	High degree of prostate related LUTS in a prospective cross-sectional community study in Ghana (Mamprobi)
title_fullStr	High degree of prostate related LUTS in a prospective cross-sectional community study in Ghana (Mamprobi)
title_full_unstemmed	High degree of prostate related LUTS in a prospective cross-sectional community study in Ghana (Mamprobi)
title_sort	high degree of prostate related luts in a prospective cross-sectional community study in ghana (mamprobi)
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/4b4165c8250043f4846c1c7e7680d957
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High degree of prostate related LUTS in a prospective cross-sectional community study in Ghana (Mamprobi)

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