Considering the Other Half of the Gut Microbiome: Bacteriophages

ABSTRACT Bacteriophages, viruses specific to bacteria, regulate bacterial communities in all known microbial systems. My research aims to determine how they interact with the trillions of bacteria found in the human gut. To do this, I apply a whole-systems perspective on both communities, considerin...

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Autor principal: Corinne F. Maurice
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Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/4b43a7a0f79b476ab6d87d841e2f963d
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spelling oai:doaj.org-article:4b43a7a0f79b476ab6d87d841e2f963d2021-12-02T19:46:18ZConsidering the Other Half of the Gut Microbiome: Bacteriophages10.1128/mSystems.00102-192379-5077https://doaj.org/article/4b43a7a0f79b476ab6d87d841e2f963d2019-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00102-19https://doaj.org/toc/2379-5077ABSTRACT Bacteriophages, viruses specific to bacteria, regulate bacterial communities in all known microbial systems. My research aims to determine how they interact with the trillions of bacteria found in the human gut. To do this, I apply a whole-systems perspective on both communities, considering bacteriophage replication cycles, bacterial and bacteriophage diversity, temporal dynamics, interactions, and responses to perturbations. Building upon ecological concepts and an array of independent and complementary techniques, I study the human gut from a microbial perspective. In contrast with bacteria, working with bacteriophage communities comes with many significant challenges, starting with the limited experimental toolkit and curated databases. Yet an increasing number of studies are pushing these scientific boundaries every day. In the human gut, future research that includes bacteriophages will lead to many exciting and warranted research avenues. From phage therapy and immunization to targeted drug delivery, the sky is the limit in my opinion.Corinne F. MauriceAmerican Society for Microbiologyarticlebacteriophagesgut microbiomemicrobial interactionsmicrobial metabolismreplication cyclesMicrobiologyQR1-502ENmSystems, Vol 4, Iss 3 (2019)
institution DOAJ
collection DOAJ
language EN
topic bacteriophages
gut microbiome
microbial interactions
microbial metabolism
replication cycles
Microbiology
QR1-502
spellingShingle bacteriophages
gut microbiome
microbial interactions
microbial metabolism
replication cycles
Microbiology
QR1-502
Corinne F. Maurice
Considering the Other Half of the Gut Microbiome: Bacteriophages
description ABSTRACT Bacteriophages, viruses specific to bacteria, regulate bacterial communities in all known microbial systems. My research aims to determine how they interact with the trillions of bacteria found in the human gut. To do this, I apply a whole-systems perspective on both communities, considering bacteriophage replication cycles, bacterial and bacteriophage diversity, temporal dynamics, interactions, and responses to perturbations. Building upon ecological concepts and an array of independent and complementary techniques, I study the human gut from a microbial perspective. In contrast with bacteria, working with bacteriophage communities comes with many significant challenges, starting with the limited experimental toolkit and curated databases. Yet an increasing number of studies are pushing these scientific boundaries every day. In the human gut, future research that includes bacteriophages will lead to many exciting and warranted research avenues. From phage therapy and immunization to targeted drug delivery, the sky is the limit in my opinion.
format article
author Corinne F. Maurice
author_facet Corinne F. Maurice
author_sort Corinne F. Maurice
title Considering the Other Half of the Gut Microbiome: Bacteriophages
title_short Considering the Other Half of the Gut Microbiome: Bacteriophages
title_full Considering the Other Half of the Gut Microbiome: Bacteriophages
title_fullStr Considering the Other Half of the Gut Microbiome: Bacteriophages
title_full_unstemmed Considering the Other Half of the Gut Microbiome: Bacteriophages
title_sort considering the other half of the gut microbiome: bacteriophages
publisher American Society for Microbiology
publishDate 2019
url https://doaj.org/article/4b43a7a0f79b476ab6d87d841e2f963d
work_keys_str_mv AT corinnefmaurice consideringtheotherhalfofthegutmicrobiomebacteriophages
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