Cyclic stretch induces cell reorientation on substrates by destabilizing catch bonds in focal adhesions.
A minimal model of cellular mechanosensing system that consists of a single stress fiber adhering on a substrate via two focal adhesions made of catch bonds is adopted to investigate the phenomena of cell reorientation on substrates induced by an applied uniaxial cyclic stretch. The model indicates...
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Autores principales: | , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Acceso en línea: | https://doaj.org/article/4b568d8ff73a42fba2274abbfc3e31a2 |
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