Rhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling

Abstract Legume plants form a root-nodule symbiosis with rhizobia. This symbiosis establishment generally relies on rhizobium-produced Nod factors (NFs) and their perception by leguminous receptors (NFRs) that trigger nodulation. However, certain rhizobia hijack leguminous nodulation signalling via...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Safirah Tasa Nerves Ratu, Albin Teulet, Hiroki Miwa, Sachiko Masuda, Hien P. Nguyen, Michiko Yasuda, Shusei Sato, Takakazu Kaneko, Makoto Hayashi, Eric Giraud, Shin Okazaki
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4b5d00fd6a9f47cf90f7484b208eed40
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4b5d00fd6a9f47cf90f7484b208eed40
record_format	dspace
spelling	oai:doaj.org-article:4b5d00fd6a9f47cf90f7484b208eed402021-12-02T15:23:47ZRhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling10.1038/s41598-021-81598-62045-2322https://doaj.org/article/4b5d00fd6a9f47cf90f7484b208eed402021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-81598-6https://doaj.org/toc/2045-2322Abstract Legume plants form a root-nodule symbiosis with rhizobia. This symbiosis establishment generally relies on rhizobium-produced Nod factors (NFs) and their perception by leguminous receptors (NFRs) that trigger nodulation. However, certain rhizobia hijack leguminous nodulation signalling via their type III secretion system, which functions in pathogenic bacteria to deliver effector proteins into host cells. Here, we report that rhizobia use pathogenic-like effectors to hijack legume nodulation signalling. The rhizobial effector Bel2-5 resembles the XopD effector of the plant pathogen Xanthomonas campestris and could induce nitrogen-fixing nodules on soybean nfr mutant. The soybean root transcriptome revealed that Bel2-5 induces expression of cytokinin-related genes, which are important for nodule organogenesis and represses ethylene- and defense-related genes that are deleterious to nodulation. Remarkably, Bel2-5 introduction into a strain unable to nodulate soybean mutant affected in NF perception conferred nodulation ability. Our findings show that rhizobia employ and have customized pathogenic effectors to promote leguminous nodulation signalling.Safirah Tasa Nerves RatuAlbin TeuletHiroki MiwaSachiko MasudaHien P. NguyenMichiko YasudaShusei SatoTakakazu KanekoMakoto HayashiEric GiraudShin OkazakiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Safirah Tasa Nerves Ratu Albin Teulet Hiroki Miwa Sachiko Masuda Hien P. Nguyen Michiko Yasuda Shusei Sato Takakazu Kaneko Makoto Hayashi Eric Giraud Shin Okazaki Rhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling
description	Abstract Legume plants form a root-nodule symbiosis with rhizobia. This symbiosis establishment generally relies on rhizobium-produced Nod factors (NFs) and their perception by leguminous receptors (NFRs) that trigger nodulation. However, certain rhizobia hijack leguminous nodulation signalling via their type III secretion system, which functions in pathogenic bacteria to deliver effector proteins into host cells. Here, we report that rhizobia use pathogenic-like effectors to hijack legume nodulation signalling. The rhizobial effector Bel2-5 resembles the XopD effector of the plant pathogen Xanthomonas campestris and could induce nitrogen-fixing nodules on soybean nfr mutant. The soybean root transcriptome revealed that Bel2-5 induces expression of cytokinin-related genes, which are important for nodule organogenesis and represses ethylene- and defense-related genes that are deleterious to nodulation. Remarkably, Bel2-5 introduction into a strain unable to nodulate soybean mutant affected in NF perception conferred nodulation ability. Our findings show that rhizobia employ and have customized pathogenic effectors to promote leguminous nodulation signalling.
format	article
author	Safirah Tasa Nerves Ratu Albin Teulet Hiroki Miwa Sachiko Masuda Hien P. Nguyen Michiko Yasuda Shusei Sato Takakazu Kaneko Makoto Hayashi Eric Giraud Shin Okazaki
author_facet	Safirah Tasa Nerves Ratu Albin Teulet Hiroki Miwa Sachiko Masuda Hien P. Nguyen Michiko Yasuda Shusei Sato Takakazu Kaneko Makoto Hayashi Eric Giraud Shin Okazaki
author_sort	Safirah Tasa Nerves Ratu
title	Rhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling
title_short	Rhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling
title_full	Rhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling
title_fullStr	Rhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling
title_full_unstemmed	Rhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling
title_sort	rhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4b5d00fd6a9f47cf90f7484b208eed40
work_keys_str_mv	AT safirahtasanervesratu rhizobiauseapathogeniclikeeffectortohijackleguminousnodulationsignalling AT albinteulet rhizobiauseapathogeniclikeeffectortohijackleguminousnodulationsignalling AT hirokimiwa rhizobiauseapathogeniclikeeffectortohijackleguminousnodulationsignalling AT sachikomasuda rhizobiauseapathogeniclikeeffectortohijackleguminousnodulationsignalling AT hienpnguyen rhizobiauseapathogeniclikeeffectortohijackleguminousnodulationsignalling AT michikoyasuda rhizobiauseapathogeniclikeeffectortohijackleguminousnodulationsignalling AT shuseisato rhizobiauseapathogeniclikeeffectortohijackleguminousnodulationsignalling AT takakazukaneko rhizobiauseapathogeniclikeeffectortohijackleguminousnodulationsignalling AT makotohayashi rhizobiauseapathogeniclikeeffectortohijackleguminousnodulationsignalling AT ericgiraud rhizobiauseapathogeniclikeeffectortohijackleguminousnodulationsignalling AT shinokazaki rhizobiauseapathogeniclikeeffectortohijackleguminousnodulationsignalling
_version_	1718387262286200832

Rhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling

Ejemplares similares