Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis

ABSTRACT: Purpose: To investigate visual-related quality of life (VRQL) and prevalence and severity of depressive symptoms in Brazilian individuals with toxoplasmic retinochoroiditis (TRC). Design: Comparative observational cross-sectional study. The National Eye Institute Visual Function Questionn...

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Autores principales:	Jacqueline Souza Dutra Arruda, Jacqueline Domingues Tibúrcio, Salvina Maria de Campos-Carli, Antônio Lucio Teixeira, Daniel Vitor Vasconcelos-Santos
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Ocular toxoplasmosis Uveitis Quality of life Depression Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/4b5f477a470f4094bda8e72300c38e89
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spelling	oai:doaj.org-article:4b5f477a470f4094bda8e72300c38e892021-11-30T04:14:00ZVision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis1201-971210.1016/j.ijid.2021.08.051https://doaj.org/article/4b5f477a470f4094bda8e72300c38e892021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1201971221006858https://doaj.org/toc/1201-9712ABSTRACT: Purpose: To investigate visual-related quality of life (VRQL) and prevalence and severity of depressive symptoms in Brazilian individuals with toxoplasmic retinochoroiditis (TRC). Design: Comparative observational cross-sectional study. The National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25) and Beck Depression Inventory-II (BDI-II) were applied to respectively assess VRQL and depression in individuals consecutively seen at a uveitis referral center. Clinical/demographical data were collected. Descriptive/analytic statistics were employed, with P<0.05. Results: Patients and controls were comparable concerning age, sex and socioeconomic level. VRQL scores for all subscales were significantly lower in TRC when compared with controls, particularly associated (P<0.05) with female sex, history of ≥2 prior TRC recurrences, concomitant use of systemic corticosteroids, monocular vision and blindness. Depressive symptoms were more prevalent in TRC (55/188; 29.2%) than in controls (34/182; 18.7%) (P=0.023), also being associated with lower VRQL scores (P<0.001). Seropositive and seronegative controls for toxoplasmosis had similar VRQL scores and comparable rates of depressive symptoms. Conclusion: TRC affects VRQL in Brazilian individuals, particularly women, using systemic corticosteroids, with visual impairment and presenting recurrences of TRC. One-third of patients with TRC had evidence of depression, which was also associated with lower VRQL scores. Mental health issues in subjects with TRC should not be overlooked.Jacqueline Souza Dutra ArrudaJacqueline Domingues TibúrcioSalvina Maria de Campos-CarliAntônio Lucio TeixeiraDaniel Vitor Vasconcelos-SantosElsevierarticleOcular toxoplasmosisUveitisQuality of lifeDepressionInfectious and parasitic diseasesRC109-216ENInternational Journal of Infectious Diseases, Vol 112, Iss , Pp 66-72 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ocular toxoplasmosis Uveitis Quality of life Depression Infectious and parasitic diseases RC109-216
spellingShingle	Ocular toxoplasmosis Uveitis Quality of life Depression Infectious and parasitic diseases RC109-216 Jacqueline Souza Dutra Arruda Jacqueline Domingues Tibúrcio Salvina Maria de Campos-Carli Antônio Lucio Teixeira Daniel Vitor Vasconcelos-Santos Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis
description	ABSTRACT: Purpose: To investigate visual-related quality of life (VRQL) and prevalence and severity of depressive symptoms in Brazilian individuals with toxoplasmic retinochoroiditis (TRC). Design: Comparative observational cross-sectional study. The National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25) and Beck Depression Inventory-II (BDI-II) were applied to respectively assess VRQL and depression in individuals consecutively seen at a uveitis referral center. Clinical/demographical data were collected. Descriptive/analytic statistics were employed, with P<0.05. Results: Patients and controls were comparable concerning age, sex and socioeconomic level. VRQL scores for all subscales were significantly lower in TRC when compared with controls, particularly associated (P<0.05) with female sex, history of ≥2 prior TRC recurrences, concomitant use of systemic corticosteroids, monocular vision and blindness. Depressive symptoms were more prevalent in TRC (55/188; 29.2%) than in controls (34/182; 18.7%) (P=0.023), also being associated with lower VRQL scores (P<0.001). Seropositive and seronegative controls for toxoplasmosis had similar VRQL scores and comparable rates of depressive symptoms. Conclusion: TRC affects VRQL in Brazilian individuals, particularly women, using systemic corticosteroids, with visual impairment and presenting recurrences of TRC. One-third of patients with TRC had evidence of depression, which was also associated with lower VRQL scores. Mental health issues in subjects with TRC should not be overlooked.
format	article
author	Jacqueline Souza Dutra Arruda Jacqueline Domingues Tibúrcio Salvina Maria de Campos-Carli Antônio Lucio Teixeira Daniel Vitor Vasconcelos-Santos
author_facet	Jacqueline Souza Dutra Arruda Jacqueline Domingues Tibúrcio Salvina Maria de Campos-Carli Antônio Lucio Teixeira Daniel Vitor Vasconcelos-Santos
author_sort	Jacqueline Souza Dutra Arruda
title	Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis
title_short	Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis
title_full	Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis
title_fullStr	Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis
title_full_unstemmed	Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis
title_sort	vision-related quality of life and depression in brazilian patients with toxoplasmic retinochoroiditis
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/4b5f477a470f4094bda8e72300c38e89
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Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis

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