Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936.

Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936.

The APOE ε and TOMM40 rs10524523 ('523') variable length poly-T repeat gene loci have been significantly and independently associated with Alzheimer's disease (AD) related phenotypes such as age of clinical onset. Hippocampal atrophy has been significantly associated with memory impai...

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Autores principales: Donald M Lyall, Natalie A Royle, Sarah E Harris, Mark E Bastin, Susana Muñoz Maniega, Catherine Murray, Michael W Lutz, Ann M Saunders, Allen D Roses, Maria C del Valdés Hernández, John M Starr, David J Porteous, Joanna M Wardlaw, Ian J Deary
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/4b656b486d5a421890436bac0f1814b1
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