Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936.

The APOE ε and TOMM40 rs10524523 ('523') variable length poly-T repeat gene loci have been significantly and independently associated with Alzheimer's disease (AD) related phenotypes such as age of clinical onset. Hippocampal atrophy has been significantly associated with memory impai...

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Auteurs principaux:	Donald M Lyall, Natalie A Royle, Sarah E Harris, Mark E Bastin, Susana Muñoz Maniega, Catherine Murray, Michael W Lutz, Ann M Saunders, Allen D Roses, Maria C del Valdés Hernández, John M Starr, David J Porteous, Joanna M Wardlaw, Ian J Deary
Format:	article
Langue:	EN
Publié:	Public Library of Science (PLoS) 2013
Sujets:	Medicine R Science Q
Accès en ligne:	https://doaj.org/article/4b656b486d5a421890436bac0f1814b1
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Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936.

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