Fissura Labiopalatina e Câncer: uma Conexão Verdadeira

Multifactorial cleft lip and palate is relatively common in populations (1 in every 700 livebirths). Individuals born with clefts require lifelong treatment after initial surgical repair and data suggested that their lifespan is shorter, possibly due to cancer or psychiatric conditions. Molecular d...

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Autor principal:	Alexandre Rezende Vieira
Formato:	article
Lenguaje:	EN PT
Publicado:	Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) 2021
Materias:	Fenda Labial Fissura Palatina Neoplasias Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/4b6a764dcf07437a8d03e19a160b777d
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id	oai:doaj.org-article:4b6a764dcf07437a8d03e19a160b777d
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spelling	oai:doaj.org-article:4b6a764dcf07437a8d03e19a160b777d2021-11-29T18:23:19ZFissura Labiopalatina e Câncer: uma Conexão Verdadeira10.32635/2176-9745.RBC.2021v67n4.23960034-71162176-9745https://doaj.org/article/4b6a764dcf07437a8d03e19a160b777d2021-09-01T00:00:00Zhttps://rbc.inca.gov.br/revista/index.php/revista/article/view/2396https://doaj.org/toc/0034-7116https://doaj.org/toc/2176-9745 Multifactorial cleft lip and palate is relatively common in populations (1 in every 700 livebirths). Individuals born with clefts require lifelong treatment after initial surgical repair and data suggested that their lifespan is shorter, possibly due to cancer or psychiatric conditions. Molecular defects that alter facial development in utero appear to later in life predispose to cancer. Common polymorphisms in e-cadherin and an endoplasmic reticulum transmembrane sensor gene appear to hold the promise to be biomarkers that may help to define individual risks to cancer, in the presence or not of family history of clefts. Alexandre Rezende VieiraInstituto Nacional de Câncer José Alencar Gomes da Silva (INCA)articleFenda LabialFissura PalatinaNeoplasiasNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENPTRevista Brasileira de Cancerologia, Vol 67, Iss 4 (2021)
institution	DOAJ
collection	DOAJ
language	EN PT
topic	Fenda Labial Fissura Palatina Neoplasias Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Fenda Labial Fissura Palatina Neoplasias Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Alexandre Rezende Vieira Fissura Labiopalatina e Câncer: uma Conexão Verdadeira
description	Multifactorial cleft lip and palate is relatively common in populations (1 in every 700 livebirths). Individuals born with clefts require lifelong treatment after initial surgical repair and data suggested that their lifespan is shorter, possibly due to cancer or psychiatric conditions. Molecular defects that alter facial development in utero appear to later in life predispose to cancer. Common polymorphisms in e-cadherin and an endoplasmic reticulum transmembrane sensor gene appear to hold the promise to be biomarkers that may help to define individual risks to cancer, in the presence or not of family history of clefts.
format	article
author	Alexandre Rezende Vieira
author_facet	Alexandre Rezende Vieira
author_sort	Alexandre Rezende Vieira
title	Fissura Labiopalatina e Câncer: uma Conexão Verdadeira
title_short	Fissura Labiopalatina e Câncer: uma Conexão Verdadeira
title_full	Fissura Labiopalatina e Câncer: uma Conexão Verdadeira
title_fullStr	Fissura Labiopalatina e Câncer: uma Conexão Verdadeira
title_full_unstemmed	Fissura Labiopalatina e Câncer: uma Conexão Verdadeira
title_sort	fissura labiopalatina e câncer: uma conexão verdadeira
publisher	Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
publishDate	2021
url	https://doaj.org/article/4b6a764dcf07437a8d03e19a160b777d
work_keys_str_mv	AT alexandrerezendevieira fissuralabiopalatinaecancerumaconexaoverdadeira
_version_	1718407160153505792

Fissura Labiopalatina e Câncer: uma Conexão Verdadeira

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