Iridium-catalyzed reductive Ugi-type reactions of tertiary amides
Chemical transformation of amides is normally occurring under harsh conditions. Here, the authors report a mild iridium-catalyzed reductive Ugi-type coupling of tertiary amides, isocyanides and (thio)acetic acid or trimethylsilyl azide to give homologous, bioactive amine products.
Guardado en:
Autores principales: | Lan-Gui Xie, Darren J. Dixon |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/4b7210f119d94a6dbf78675cb6192eb4 |
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