Sortase-mediated segmental labeling: A method for segmental assignment of intrinsically disordered regions in proteins

A significant number of proteins possess sizable intrinsically disordered regions (IDRs). Due to the dynamic nature of IDRs, NMR spectroscopy is often the tool of choice for characterizing these segments. However, the application of NMR to IDRs is often hindered by their instability, spectral overla...

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Autores principales: Kristina V. Boyko, Erin A. Rosenkranz, Derrick M. Smith, Heather L. Miears, Melissa Oueld es cheikh, Micah Z. Lund, Jeffery C. Young, Patrick N. Reardon, Mark Okon, Serge L. Smirnov, John M. Antos
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/4b834167ff064d10b997205d67b2a00d
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