Putative E3 Ubiquitin Ligase of Human Rotavirus Inhibits NF-κB Activation by Using Molecular Mimicry To Target β-TrCP
ABSTRACT NF-κB plays a critical role in the induction and maintenance of innate and adaptive immune transcriptional programs. An associated inhibitor of κB protein (IκB) regulates NF-κB activation and contains a degron motif (DSGΦxS) that undergoes phosphorylation following pathogen recognition or...
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| Main Authors: | , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2015
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| Subjects: | |
| Online Access: | https://doaj.org/article/4b88cd1bab5144a2ae6cd96cc7cccc8d |
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