Deregulation of mitochondria-shaping proteins Opa-1 and Drp-1 in manganese-induced apoptosis.

Mitochondria are dynamic organelles that undergo fusion and fission processes. These events are regulated by mitochondria-shaping proteins. Changes in the expression and/or localization of these proteins lead to a mitochondrial dynamics impairment and may promote apoptosis. Increasing evidence corre...

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Auteurs principaux: Agustina Alaimo, Roxana M Gorojod, Juan Beauquis, Manuel J Muñoz, Flavia Saravia, Mónica L Kotler
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/4b8b596b35b64ab7afd21e5e8a6acc72
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