Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants

Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants

Cerebral small vessel disease (CSVD) is a major cause of stroke and associated with structural changes of the brain. Here, Persyn et al. perform genome-wide association studies for magnetic resonance imaging (MRI) markers of CSVD, explore genetic correlations and prioritize candidate genes.

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Detalles Bibliográficos
Autores principales: Elodie Persyn, Ken B. Hanscombe, Joanna M. M. Howson, Cathryn M. Lewis, Matthew Traylor, Hugh S. Markus
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/4b8db19125ab427f99c1e646996c08e1
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Descripción
Sumario:Cerebral small vessel disease (CSVD) is a major cause of stroke and associated with structural changes of the brain. Here, Persyn et al. perform genome-wide association studies for magnetic resonance imaging (MRI) markers of CSVD, explore genetic correlations and prioritize candidate genes.

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