Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants

Cerebral small vessel disease (CSVD) is a major cause of stroke and associated with structural changes of the brain. Here, Persyn et al. perform genome-wide association studies for magnetic resonance imaging (MRI) markers of CSVD, explore genetic correlations and prioritize candidate genes.

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Autores principales: Elodie Persyn, Ken B. Hanscombe, Joanna M. M. Howson, Cathryn M. Lewis, Matthew Traylor, Hugh S. Markus
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/4b8db19125ab427f99c1e646996c08e1
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spelling oai:doaj.org-article:4b8db19125ab427f99c1e646996c08e12021-12-02T17:33:14ZGenome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants10.1038/s41467-020-15932-32041-1723https://doaj.org/article/4b8db19125ab427f99c1e646996c08e12020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15932-3https://doaj.org/toc/2041-1723Cerebral small vessel disease (CSVD) is a major cause of stroke and associated with structural changes of the brain. Here, Persyn et al. perform genome-wide association studies for magnetic resonance imaging (MRI) markers of CSVD, explore genetic correlations and prioritize candidate genes.Elodie PersynKen B. HanscombeJoanna M. M. HowsonCathryn M. LewisMatthew TraylorHugh S. MarkusNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Elodie Persyn
Ken B. Hanscombe
Joanna M. M. Howson
Cathryn M. Lewis
Matthew Traylor
Hugh S. Markus
Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants
description Cerebral small vessel disease (CSVD) is a major cause of stroke and associated with structural changes of the brain. Here, Persyn et al. perform genome-wide association studies for magnetic resonance imaging (MRI) markers of CSVD, explore genetic correlations and prioritize candidate genes.
format article
author Elodie Persyn
Ken B. Hanscombe
Joanna M. M. Howson
Cathryn M. Lewis
Matthew Traylor
Hugh S. Markus
author_facet Elodie Persyn
Ken B. Hanscombe
Joanna M. M. Howson
Cathryn M. Lewis
Matthew Traylor
Hugh S. Markus
author_sort Elodie Persyn
title Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants
title_short Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants
title_full Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants
title_fullStr Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants
title_full_unstemmed Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants
title_sort genome-wide association study of mri markers of cerebral small vessel disease in 42,310 participants
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/4b8db19125ab427f99c1e646996c08e1
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